Relationship between Non-Alcoholic Fatty Liver Disease and Cardiovascular and Metabolic Risk Indices

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dc.contributor.authorSubaşı, Huriye Ecem
dc.contributor.authorDemir, Şevin
dc.date.accessioned2024-07-12T22:04:24Z
dc.date.available2024-07-12T22:04:24Z
dc.date.issued2022en_US
dc.description.abstractIntroduction: While non-alcoholic fatty liver disease (NAFLD) is linked to other metabolic dysfunction, it may also occur alone. In our study, we investigate the factors associated with NAFLD in subjects that do not have metabolic syndrome. Materials and Methods: The files of the patients that applied to our check-up outpatient clinic were evaluated retrospectively, and patients who met the criteria for admission to the study were divided into those with and without NAFLD (n=277 and n=280, respectively) with the age variable being adjusted. Anthropometric and biochemical values, fibrosis scores, cardiovascular and metabolic risk indices were compared between groups. Results: Between individuals with and without NAFLD there were statistically significant differences in terms of waist circumference (WC), waist-hip ratio (WHR), body mass index (BMI), ALT, AST/ALT, uric acid, smoking status, lipid levels, Triglyceride/HDL, hemoglobin, homeostasis model assessment insulin resistance (HOMA-IR), triglyceride-glucose index (TyG), visceral adiposity index (VAI) parameters (p<0.005). When people with BMI<25 kg/m2 were considered, the difference between smoking, total and LDL cholesterol, ALT, AST/ALT, and HOMA-IR values lost their significance. In the group with BMI?25 kg/m2, significant differences remained only in terms of WC, WHR and BMI. It has been observed that hepatosteatosis has a positive correlation with the values of VAI, TyG, Triglyceride/HDL and AST-platelet ratio index and a negative correlation with AST/ALT. Conclusion: While cardiovascular and metabolic risk indicators were significantly increased in lean individuals with NAFLD, the increase in those risks in overweight individuals was independent of fatty liver.en_US
dc.identifier.doi10.5505/vtd.2022.76753
dc.identifier.endpage282en_US
dc.identifier.issn1300-2694
dc.identifier.issn2587-0351
dc.identifier.issue3en_US
dc.identifier.startpage275en_US
dc.identifier.trdizinid1124257en_US
dc.identifier.urihttps://doi.org/10.5505/vtd.2022.76753
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1124257
dc.identifier.urihttps://hdl.handle.net/20.500.12415/9731
dc.identifier.volume29en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofVan Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY05095
dc.titleRelationship between Non-Alcoholic Fatty Liver Disease and Cardiovascular and Metabolic Risk Indicesen_US
dc.typeArticle
dspace.entity.typePublication

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