A Retrospective Evaluation of the Laboratory Findings of Dermatology Patients Whose Biotin Levels Were Checked

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dc.contributor.authorGüder, Hüsna
dc.contributor.authorEker, Pınar
dc.date.accessioned2024-07-12T21:40:17Z
dc.date.available2024-07-12T21:40:17Z
dc.date.issued2023en_US
dc.department[Belirlenecek]en_US
dc.description.abstractObjective Biotin is widely known to be beneficial for the hair, nails, and skin, but there are only a few studies on biotin. We evaluated whether there is a relationship between biotin levels and age, gender, and frequently observed laboratory findings. We also evaluated biotin levels according to the reason for checking biotin levels. Methods One hundred five patients applied to the dermatology outpatient clinic and had their biotin levels checked. Patient files were retrospectively analyzed. Results There were a weak positive (r=0.207) relationship between biotin levels and basophil count, a weak positive (r=0.201) relationship between biotin levels and creatinine, and a weak positive (r=0.314) relationship between biotin levels and cholesterol/triglyceride ratio. There were a weak negative (r=-0.216) relationship between biotin levels and mean platelet volume (MPV) and a moderately negative (r=-0.315) relationship between biotin levels and triglyceride levels. Conclusion Biotin levels do not significantly differ with gender but increase with age. Although a weak correlation was detected between hemogram parameters and biotin levels with basophil percentage and mean platelet volume values, biotin did not significantly change hemogram parameters. The relationship between biotin levels and triglyceride levels was the most critical finding of our study. We recommend examining biotin levels in the patients with high triglyceride levels. When we encounter dermatological side effects related to the use of epidermal growth factor receptor tyrosine kinase inhibitors, we recommend evaluating biotin levels. We recommend that biotin supplementation be made only in the patients with deficiencies and that biotin levels be measured in the follow-up.en_US
dc.identifier.doi10.7759/cureus.41482
dc.identifier.issn2168-8184
dc.identifier.issue7en_US
dc.identifier.pmid37551230en_US
dc.identifier.urihttps://doi.org/10.7759/cureus.41482
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7221
dc.identifier.volume15en_US
dc.identifier.wosWOS:001124244700003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.ispartofCureus Journal of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY05159
dc.subjectLaboratory Findingsen_US
dc.subjectSkin Conditionsen_US
dc.subjectVitaminsen_US
dc.subjectTriglycerideen_US
dc.subjectBiotinen_US
dc.titleA Retrospective Evaluation of the Laboratory Findings of Dermatology Patients Whose Biotin Levels Were Checkeden_US
dc.typeArticle
dspace.entity.typePublication

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