‘Ovarian rest’ between induction cycles of poor responder patients in assisted reproduction programmes

dc.authorid0000-0003-4563-3592en_US
dc.contributor.authorKüçük, T.
dc.contributor.authorPabuçcu, Recai
dc.contributor.authorOrhon, E.
dc.contributor.authorDuru, Namık Kemal
dc.date.accessioned2024-07-12T21:04:05Z
dc.date.available2024-07-12T21:04:05Z
dc.date.issued1997en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractIntroduction: Since Cohen et al. reported the first pregnancy after mechanical partial zona dissection, this micromanipulation technique has been used routinely to enhance the chance of fertilizing the ovum in instances of poor sperm quality. Recently, micromanipulation has been performed to facilitate embryo hatching. Women with genital tuberculosis appear to represent a less favourable subset within other tubal factor patients when treated with IVF. Not only the tubal factor but also the lack of a recipient endometrium may cause disappointing results in this group of infertile women. Materials and methods: The study included 14 cases of tuberculosis, evaluated with hysteroscopy, endometrial biopsy and an acid-fast bacilli stain before treatment with IVF and embryo transfer. All had ovarian stimulation under pituitary desensitization with long protocol GnRHa. FOllowing 2 or 3. days of incubation, all embryos underwent mechanically assisted hatching using a microinjection pipette at the 4- to 8- cell stage. Prior to embryo transfer they were incubated for a further 2 h. Luteal phase support was achieved with progesterone vaginal suppositories. Results: Of the 14 patients, 12 (85.7%) achieved pregnancy in the first cycle. Each woman had three or four hatched embryos transferred. The implantation rate per hatched embryo was 39.5%. Conclusion: Compared with unhatched embryo transfer results, the surprisingly high rate of pregnancy in our series suggests that women with tuberculosis are lacking not only a receptive endometrium but also possibly a factor that may physiologically induce hatching.en_US
dc.identifier.citationKüçük, T., Pabuçcu, R., Orhon, E., Duru, N. K. ve Cıncık, M. (1997). ‘Ovarian rest’ between induction cycles of poor responder patients in assisted reproduction programmes. Human Reproduction, Oxford Academic. 12(2), s. 254.en_US
dc.identifier.endpage254en_US
dc.identifier.issn1460-2350
dc.identifier.issn0268-1161
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage254en_US
dc.identifier.urihttps://academic.oup.com/humrep/article/12/Suppl_2/254/2486887
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3751
dc.identifier.volume12en_US
dc.institutionauthorCıncık, Mehmet
dc.language.isoenen_US
dc.publisherOxford Academicen_US
dc.relation.ispartofHuman Reproductionen_US
dc.relation.isversionof10.1093/humrep/12.Suppl_2.254-aen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY01196
dc.title‘Ovarian rest’ between induction cycles of poor responder patients in assisted reproduction programmesen_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar