Ultrastructural and histochemical characterization of secretory granules in human lung adenocarcinoma cells
Küçük Resim Yok
Tarih
2000
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cambridge University Press
Erişim Hakkı
CC0 1.0 Universal
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Histochemical methods offer an excellent research tool for the characterization of glycoproteins in the secretory cells, thus contributing to the elucidation of the pathophysiology of different diseases. The different staining characteristics of mucins can be useful in diagnostic histopathology. It has been proposed that the reduction in sulphated glycoproteins and an increase in sialomucins in intestinal mucosa was an indicator of premalignant changes in carcinoma of the bowel. It has subsequently argued that this change may be consequence rather than a precursor of neoplasia. It may still be of some value as a marker of a premalignant change although it is somewhat variable. Previous studies have demonstrated the characterization of glycoproteins in different type of epitheloid cells in normal and pathologic conditions by using histochemical and electron microscopic techniques. However; little information has been available concerning the exact features of secretory granules in both normal and tumoral cells in lung.
Açıklama
Anahtar Kelimeler
Kaynak
Microscopy & Microanalysis
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
6
Sayı
2
Künye
Aktas, R.G., Demiralay, E., Altaner, S., Candan, L. ve Kutlu, A.K. (2000). Ultrastructural and histochemical characterization of secretory granules in human lung adenocarcinoma cells. Microscopy & Microanalysis, Cambridge University Press. 6(2), s. 480-481.
