Objective measures of sleep in fibromyalgia syndrome: Relationship to clinical, psychiatric, and immunological variables

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dc.contributor.authorÇetin B.
dc.contributor.authorGüleç H.
dc.contributor.authorToktaş H.E.
dc.contributor.authorUlutaş Ö.
dc.contributor.authorYılmaz S.G.
dc.contributor.authorİsbir T.
dc.date.accessioned2024-07-12T21:52:56Z
dc.date.available2024-07-12T21:52:56Z
dc.date.issued2018en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractWe aimed to investigate the changes in the objective and subjective sleep variables during painful episodes of fibromyalgia and post-episode period, and to evaluate the impact of the sleep variables on the current clinical, psychological, and immunologic parameters. Thirty-one consecutive patients who were referred to the Erenköy Physical Therapy and Rehabilitation Polyclinic with a diagnosis of fibromyalgia were evaluated before and in the sixth week of the acute pain treatment. The sleep variables were measured by polysomnography, Pittsburgh Sleep Quality Index, and Epworth Sleepiness Scale. The clinical and psychiatric assessment of patients was performed by using Fibromyalgia Impact Questionnaire; Patient Health Questionnaire-Somatic, Anxiety, and Depressive Symptoms; and Visual Analog Scale. Serum pro-inflammatory molecules were measured to evaluate the immunological status. The pain treatment significantly affected subjective sleep variables, psychiatric variables, clinical variables, and IL-6 levels. The subjective sleep parameters, clinical and psychiatric variables, and IL-6 levels were improved with pain treatment in fibromyalgia. The objective sleep variables, IL-1 and TNF-alpha levels were not significantly improved with the pain treatment, and they were not related to clinical presentation of patients with fibromyalgia. Subjective variability of sleep contributes to the clinical presentation, suggesting that the objective structure is trait-specific with IL-1 and TNF-alpha. © 2018 Elsevier B.V.en_US
dc.identifier.doi10.1016/j.psychres.2018.02.057
dc.identifier.endpage129en_US
dc.identifier.issn0165-1781
dc.identifier.pmid29549784en_US
dc.identifier.scopus2-s2.0-85054062744en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage125en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.psychres.2018.02.057
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8444
dc.identifier.volume263en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofPsychiatry Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY03320
dc.titleObjective measures of sleep in fibromyalgia syndrome: Relationship to clinical, psychiatric, and immunological variablesen_US
dc.typeArticle
dspace.entity.typePublication

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