Autologous fat augmentation for voice and swallow improvement after cordectomy

Basit Öğe Kaydı
dc.authorid0000-0001-7914-2201en_US
dc.contributor.authorGüven, Mehmet
dc.contributor.authorSüoğlu, Yusufhan
dc.contributor.authorKıyak, Erkan
dc.contributor.authorDemir, Deniz
dc.contributor.authorDemir, Deniz
dc.date.accessioned2024-07-12T21:00:37Z
dc.date.available2024-07-12T21:00:37Z
dc.date.issued2006en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractSurgery for the treatment of early-stage glottic carcinoma still remains a valid option. In most patients, newly formed neocord tissue preserves glottic functions, but in some patients an important glottic gap leading to glottic insufficiency may occur. In our study, 11 patients who had serious glottic insufficiency after endoscopic laser and laryngofissure cordectomy were treated with autologous fat injection (AFI) into the neocord tissue for voice and swallowing rehabilitation. One patient did not attend the first control visit and was excluded from the study. The remaining 10 patients were evaluated in the preoperative and postoperative periods for phonatory functions and efficacy of AFI by videolaryngostroboscopy and computerized acoustic analysis. Phonatory functions showed statistically significant improvement in the shimmer, noise-to-harmonic ratio, maximum phonation time and fundamental frequency. Perceptual ratings (GRBAS scale) also showed statistically significant improvement in all 5 parameters. Despite improvement in glottic closure, the mucosal wave deteriorated. Due to recurrence of symptoms of glottic insufficiency, AFI was repeated in 2 patients at the third and fifth months, respectively. One year later, the AFI resulted in successful rehabilitation of swallowing in all patients. The probability of resorption of autologous fat and the deterioration of the mucosal wave after AFI remain a problem, but re-injection can be done easily. As AFI is an easy, safe and cheap method, we concluded that it is a promising alternative procedure for managing voice problems after laser or laryngofissure cordectomy defects.en_US
dc.identifier.citationGüven, M., Süoğlu, Y., Kıyak, E. ve Demir, D. (2006). Autologous fat augmentation for voice and swallow improvement after cordectomy. Journal for Oto-Rhino-Laryngology, Head and Neck Surgery, Karger. 68(3), s. 164-169.en_US
dc.identifier.endpage169en_US
dc.identifier.issn1423-0275
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage164en_US
dc.identifier.urihttps://www.karger.com/Article/Abstract/91342
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3403
dc.identifier.volume68en_US
dc.institutionauthorDemir, Deniz
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofJournal for Oto-Rhino-Laryngology, Head and Neck Surgeryen_US
dc.relation.isversionof10.1159/000091342en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01779
dc.subjectCordectomyen_US
dc.subjectLaryngofissureen_US
dc.subjectAutologous faten_US
dc.subjectNeocord tissueen_US
dc.subjectMucosal waveen_US
dc.titleAutologous fat augmentation for voice and swallow improvement after cordectomyen_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar

Koleksiyon

Tıp Fakültesi Koleksiyonu