Abnormal aortic elasticity in patients with liver steatosis

dc.authorid0000-0002-5634-1280en_US
dc.authorid0000-0003-1407-5313en_US
dc.authorid0000-0002-2858-4023en_US
dc.authorid0000-0001-7261-2397en_US
dc.contributor.authorIşılak, Zafer
dc.contributor.authorAparcı, Mustafa
dc.contributor.authorKardeşoğlu, Ejder
dc.contributor.authorYiğiner, Ömer
dc.contributor.authorUz, Ömer
dc.contributor.authorSıldıroğlu, Onur Hüseyin
dc.contributor.authorÖzmen, Namık
dc.contributor.authorYalçın, Murat
dc.contributor.authorCebeci, Bekir Sıtkı
dc.date.accessioned2024-07-12T21:03:18Z
dc.date.available2024-07-12T21:03:18Z
dc.date.issued2010en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractAim Non-alcoholic fatty liver disease (NAFLD) may be associated with insulin resistance. We aimed to evaluate elastic properties of aorta in patients with NAFLD. Material and method Ninety-two patients with NAFLD and 47 healthy subjects were performed ultrasonographic and echocardiographic examination. Aortic stiffness index (ASI), aortic distensibility (AD) and aortic strain (AS) were compared between healthy subjects and patients and also among grade I and II liver steatosis. Statistical analysis was performed by Independent-Samples t-test, Pearson's correlation test using SPSS 11.0. Results ASI was significantly increased whereas AS and AD were reduced (p > 0.05) in patients compared to normal ones. ASI was significantly increased while AD and AS slightly increased in patients with grade II liver steatosis compare to grade I. SBP and DBP, cholesterol levels, fasting blood glucose (FBG) were also increased and doppler flow parameters of mitral inflow were abnormally changed in those patients. ASI was positively correlated with FBG, ALT and ALP levels, LDL cholesterol, heart rate and deceleration time of mitral E wave. Conclusion Elastic properties of aorta were abnormally changed in patients with NAFLD. Multiple hemodynamic abnormalities probably associated with insulin resistance may be accountable for abnormal elastic properties of aorta.en_US
dc.identifier.endpage50en_US
dc.identifier.issn0168-8227
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage44en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0168822709004343
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3656
dc.identifier.volume87en_US
dc.institutionauthorCingözbay, Bekir Yılmaz
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofDiabetes Research and Clinical Practiceen_US
dc.relation.isversionof10.1016/j.diabres.2009.10.009en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY00636
dc.subjectLiver steatosisen_US
dc.subjectAortaen_US
dc.subjectInsulin resistanceen_US
dc.subjectCholesterolen_US
dc.subjectInflammationen_US
dc.titleAbnormal aortic elasticity in patients with liver steatosisen_US
dc.typeArticle
dspace.entity.typePublication

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