DNA ploidy, proliferative activity, and concanavalin A reactivity in breast cancer

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dc.authorid0000-0002-8335-1927en_US
dc.contributor.authorPaydaş, Semra
dc.contributor.authorSarpel, Süleyman
dc.contributor.authorGilman Sachs, Alice
dc.contributor.authorTuncer, İlhan
dc.contributor.authorPehlivan, Sacide
dc.contributor.authorTunalı, Nurdan
dc.contributor.authorZorludemir, Suzan
dc.contributor.authorBurgut, Hüseyin Refik
dc.contributor.authorKüçük, Ömer
dc.date.accessioned2024-07-12T21:04:56Z
dc.date.available2024-07-12T21:04:56Z
dc.date.issued1994en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractParaffin?embedded primary tumor specimens from 48 patients with breast cancer were examined for DNA ploidy, S?phase fraction (SPF), and concanavalin A (Con A) reactivity. The results were correlated with clinicopathological prognostic factors, including patients' age and menopausal status, stage of disease, nuclear grade, and size of the primary tumor. There were no associations among ploidy, SPF, Con A reactivity, and menopausal status, stage of disease, or size of the primary tumor. However, among patients who were 50 years or older, 81 % had diploid tumors and 73% had good reactivity (3+ or better staining score) with Con A. In contrast, among patients who were younger than 50 years, 45% had diploid tumors (P < 0.05) and 21% had good Con A reactivity (P < 0.05). Seven of 19 (37%) poorly differentiated tumors and 7 of 9 (78%) moderately differentiated tumors had good reactivity with Con A (P < 0.05). Reactivity of tumor cells with Con A in primary breast cancer tissues deserves further evaluation as a potential biomarker of prognosis. © 1994 Wiley?Liss, Inc.en_US
dc.identifier.citationPaydaş, S., Sarpel, S., Gilman Sachs, A., Tuncer, İ., Pehlivan, S., Tunalı, N., Zorludemir, S., Burgut, H. R. ve Küçük, Ö. (1994). DNA ploidy, proliferative activity, and concanavalin A reactivity in breast cancer. Journal of Surgical Oncology. 56(1), s. 21-24.en_US
dc.identifier.endpage24en_US
dc.identifier.issn1096-9098
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3855
dc.identifier.volume56en_US
dc.institutionauthorBurgut, Hüseyin Refik
dc.language.isoenen_US
dc.publisherWiley Online Libraryen_US
dc.relation.ispartofJournal of Surgical Oncologyen_US
dc.relation.isversionof10.1002/jso.2930560106en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02051
dc.titleDNA ploidy, proliferative activity, and concanavalin A reactivity in breast canceren_US
dc.typeArticle
dspace.entity.typePublication

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