Total koroner tıkanmanın PTCA ile revaskularize edildiği hastalarda QT dispersiyonundaki değişim
Küçük Resim Yok
Tarih
1999
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mebas Basın Yayın ve Tanıtım Ajans San. ve Tic. Ltd. Şti.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
İskemi ventrikül repolarizasyonunda bölgesel bozulmaya neden olarak QT dispersiyonunda (QTD= QT maximum - QT minimum) artışa neden olur. AMAÇ:Çalışmamızın amacı miyokard infarktüsü geçirmiş koroner anjiografide total koroner tıkanması olan semptomatik hastalarda anjioplasti (PTCA) ile revaskularizasyonun ve restenozun QTD üzerindeki etkisini araştırmaktı. YÖNTEM: Bu amaçla başarılı olarak revaskularize edilmiş 34 hasta (11 kadın ortalama yaş:64±5; 23 erkek ortalama yaş:59±7) çalışmaya alındı. Hastaların tamamına PTCA dan sonra 6. ayda restenozu belirlemek için koroner anjiografi yapıldı. OTO ve QTcD (kalp hızına göre Bazett formülü ile düzeltilmiş QTD) PTCA'dan 1 gün önce, 1 gün ve 6 ay sonra alınan istirahat elektrokardiyografilerinden (EKG) Image Tool (2.0 versiyon) programı kullanılarak bilgisayarda hesaplandı. BULGULAR: Ortalama QTD ve QTcD PTCA'dan bir gün sonra anlamlı derecede kısaldı (QTD (ms): 63±13 versus 46±9; QTcD: 65±13 versus 49±8 p<0,05). 6.ayda yapılan koroner anjiografide 12 hastada restenoz belirlendi (4 kadın - 8 erkek; ortalama yaş: 61±6). Restenozlu hastalarda PTCA sonrası 1.gün ile kıyaslandığında 6.ayda QTD ve QTcD'nin anlamlı derecede artmıştı (QTD(ms): 48±8 - 65±8; QTcD: 50±9 - 74±13; p<0,05). Aynı zamanda restenozlu hastaların 6.aydaki QTD ve QTcD'lerinin restenozu olmayan hastalardan anlamlı derecede yüksek olduğunu gözledik. (QTD: 65±8 - 39±7; QTcD: 74±13 - 44±7.p<0,05). SONUÇ: Bu sonuçlara göre başarılı revaskülarizasyon miyokard infarktüsü geçirmiş semptomatik olgularda QTD ve QTcD'yi kısalttığı ve restenoz QTD ve QTcD'yi uzattığı için revaskularize edilecek hastalarda QTD ve QTcD'nin izlenmesi restenozu tahminde faydalı olabilir.
Because ischemia is associated with regional abnormalities of repolarization, it increases QT dispersion (QTD= QT maximum - QT minimum). AIMS: The objective of our study was to determine the influence of revascularization on QT dispersion in symptomatic patients who had prior myocardial infarction and were determined total coronary occlusion in coronary angiography, and to detect the effect of restenosis on QT disperison. METHOD: To the purpose, 34 patients (11 female mean age: 64±5; 23 male mean age:59±7) successfully revascularized with PTCA were included in this study and coronary angiography was performed to all patients for diagnosis of restenosis in sixth month after PTCA. The QTD and QTcD (heart rate corrected QTD according to Bazett formula) were calculated from rest ECG (one day before, one day and six month after PTCA) with the software of Image Tool (2.0 version) in computer. RESULTS: Mean QTD and QTcD significantly decreased in first day after PTCA (QTD (ms): 63±13 versus 46±9; QTcD: 65±13 versus 49±8 p<0,05). In sixth month, restenosis were determined in 12 patients (4 female - 8 male; mean ages 61±6) with coronary angiography. QTD and QTcD significantly increased in sixth month when compared to first day after PTCA in patients with restenosis (QTD(ms): 48±8 versus 61±8; QTcD: 50±9 versus 74±13; p<0,05). We also observed that QTD and QTcD at sixth month of patients with restenosis were significantly higher than without restenosis (QTD: 65±8 versus 39±7; QTcD: 74±13 versus 44±7.p<0,05). CONCLUSION: Because successfully revascularization decreases QT dispersion in symptomatic patients with prior myocardial infarction and restenosis increases QT dispersion, QT dispersion monitorization in patients who will be revascularized may be beneficial in prediction of restenosis.
Because ischemia is associated with regional abnormalities of repolarization, it increases QT dispersion (QTD= QT maximum - QT minimum). AIMS: The objective of our study was to determine the influence of revascularization on QT dispersion in symptomatic patients who had prior myocardial infarction and were determined total coronary occlusion in coronary angiography, and to detect the effect of restenosis on QT disperison. METHOD: To the purpose, 34 patients (11 female mean age: 64±5; 23 male mean age:59±7) successfully revascularized with PTCA were included in this study and coronary angiography was performed to all patients for diagnosis of restenosis in sixth month after PTCA. The QTD and QTcD (heart rate corrected QTD according to Bazett formula) were calculated from rest ECG (one day before, one day and six month after PTCA) with the software of Image Tool (2.0 version) in computer. RESULTS: Mean QTD and QTcD significantly decreased in first day after PTCA (QTD (ms): 63±13 versus 46±9; QTcD: 65±13 versus 49±8 p<0,05). In sixth month, restenosis were determined in 12 patients (4 female - 8 male; mean ages 61±6) with coronary angiography. QTD and QTcD significantly increased in sixth month when compared to first day after PTCA in patients with restenosis (QTD(ms): 48±8 versus 61±8; QTcD: 50±9 versus 74±13; p<0,05). We also observed that QTD and QTcD at sixth month of patients with restenosis were significantly higher than without restenosis (QTD: 65±8 versus 39±7; QTcD: 74±13 versus 44±7.p<0,05). CONCLUSION: Because successfully revascularization decreases QT dispersion in symptomatic patients with prior myocardial infarction and restenosis increases QT dispersion, QT dispersion monitorization in patients who will be revascularized may be beneficial in prediction of restenosis.
Açıklama
Anahtar Kelimeler
PTCA, Arteriyel tıkayıcı hastalıklar, Koroner anjiyografi, Anjiyoplasti, transluminal, perkutan koroner, Restenoz, Elektrokardiyografi, QT dispersiyonu, Koroner tıkanıklık, Miyokard enfarktüsü, Revaskülarizasyon, Electrocardiography, Coronary Angiography, QT dispersion, Coronary occlusion, Myocardial Infarction, PTCA, Arterial Occlusive Diseases, Angioplasty, Transluminal, Percutaneous Coronary, Restenosis, Revascularization
Kaynak
MN Kardiyoloji
WoS Q Değeri
Scopus Q Değeri
Cilt
6
Sayı
6
Künye
Altınmakas, S., Dağdeviren, B., Uyan, C., Keser, N., Bulut, Ş. ve Pektaş, O. (1999). Total koroner tıkanmanın PTCA ile revaskularize edildiği hastalarda QT dispersiyonundaki değişim / The effect of revascularization with PTCA in total coronary occlusion QT dispersion. MN Kardiyoloji, Mebas Basın Yayın ve Tanıtım Ajans San. ve Tic. Ltd. Şti.. 6(6), s. 390-393.
