Botulinum toxin in the treatment of trigeminal neuralgia: 6-Month follow-up

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dc.contributor.authorTürk Börü Ü.
dc.contributor.authorDuman A.
dc.contributor.authorBölük C.
dc.contributor.authorCoşkun Duman S.
dc.contributor.authorTaşdemir M.
dc.date.accessioned2024-07-12T21:52:01Z
dc.date.available2024-07-12T21:52:01Z
dc.date.issued2017en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractBackground: Botulinum toxin type-A (BTX-A) has been successfully utilized to treat trigeminal neuralgia. In this study, through the use of a new technique, the efficacy of the injection of BTX-A to the maxillary and mandibular nerves was evaluated. Methods: A total of 27 patients were injected with 100 Units of BTX-A to the maxillary and mandibular nerves. Visual analogue scale score and pain frequency were assessed before treatment and at the first week, second month, and sixth month after treatment. Patients with ?50% reduction in mean pain score at the second and sixth month were defined as responders. Results: A total of 27 patients were included in the study. BTX-A significantly reduced pain intensity and pain attack frequency at the first week, second month, and sixth month after treatment. At the second month, 74.1% of patients, at the sixth month, 88.9% of patients responded to treatment. Forty-four percent of patients did not experience any pain at the sixth month. The mean recurrence period was 87.7±20.4. BTX-A was well tolerated and showed few treatment-related adverse events. Conclusion: Injection to the maxillary and mandibular roots seems to be a highly effective method. In the event of recurrence, after each injection, the pain severity and attack frequency decreased. Copyright © 2017 the Author(s). Published by Wolters Kluwer Health, Inc.en_US
dc.identifier.doi10.1097/MD.0000000000008133
dc.identifier.issn0025-7974
dc.identifier.issue39en_US
dc.identifier.pmid28953646en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://dx.doi.org/10.1097/MD.0000000000008133
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8340
dc.identifier.volume96en_US
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.relation.ispartofMedicine (United States)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY02900
dc.subjectbotulinum toxinen_US
dc.subjecttreatmenten_US
dc.subjecttrigeminal neuralgiaen_US
dc.titleBotulinum toxin in the treatment of trigeminal neuralgia: 6-Month follow-upen_US
dc.typeArticle
dspace.entity.typePublication

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