Reliability of posterior-left atrium space index measurements during 20-24 weeks of gestation in structurally normal fetuses

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dc.contributor.authorAkkurt M.O.
dc.contributor.authorYavuz A.
dc.contributor.authorAkkurt I.
dc.contributor.authorKarakoc G.
dc.contributor.authorSezik M.
dc.date.accessioned2024-07-12T21:51:19Z
dc.date.available2024-07-12T21:51:19Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractWe aimed to evaluate the correlation between clinical parameters and the post-left atrium (LA) space index, which is a candidate screening marker for total anomalous pulmonary venous connection (TAPVC). We also calculated the inter- and intra-observer variabilities of measurements for this parameter. The LA-descending aorta distance/descending aorta diameter ratios (post-LA space index) were obtained from 165 fetuses between 20 and 24 weeks of gestation. Regression analyses were utilized to evaluate the correlations across clinical parameters and the post-LA space index. Intraclass correlations coefficients were calculated for the intra- and inter-observer agreements of three examiners with different sonographic experience. The mean (±SD) maternal and gestational age (GA) was 28.6±4.9 years and 21.7±0.9 weeks of gestation, respectively. In multivariate analyses, there was no correlation between post-LA space index and maternal age, fetal gender, or GA at cardiac scan. There were moderate to strong correlations across the measurements by different examiners, indicating good inter- and intra-observer agreements. The post-LA space index during 20-24 weeks of gestation is a simple and reliable marker that is not affected by GA. However, its potential as a screening tool for TAPVC warrants further clinical investigation. © 2016 2016 Walter de Gruyter GmbH, Berlin/Boston.en_US
dc.identifier.doi10.1515/jpm-2015-0147
dc.identifier.endpage617en_US
dc.identifier.issn0300-5577
dc.identifier.issue6en_US
dc.identifier.pmid26352074en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage613en_US
dc.identifier.urihttps://dx.doi.org/10.1515/jpm-2015-0147
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8256
dc.identifier.volume44en_US
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWalter de Gruyter GmbHen_US
dc.relation.ispartofJournal of Perinatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02013
dc.subjectAntenatal diagnosisen_US
dc.subjectcongenital heart defecten_US
dc.subjectfetal echocardiogramen_US
dc.subjecttotal anomalous pulmonary venous connectionen_US
dc.titleReliability of posterior-left atrium space index measurements during 20-24 weeks of gestation in structurally normal fetusesen_US
dc.typeArticle
dspace.entity.typePublication

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