Does Flumazenil effect the anesthetic agents other than benzodiazepines?: Case report [Flumazenil benzodiazepinler dişindaki anestezik ajanlari da etkiler mi?: Olgu sunumu]

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dc.authorid0000-0002-7776-109Xen_US
dc.authorid0000-0003-3211-4945en_US
dc.contributor.authorŞentürk Ö.
dc.contributor.authorSelvi O.
dc.contributor.authorÖzer Z.
dc.date.accessioned2024-07-12T21:44:53Z
dc.date.available2024-07-12T21:44:53Z
dc.date.issued2015en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractFlumazenil is an imidazobenzodiazepine which is used to reverse sedative and hypnotic effects of benzodiazepines. Although reversing effect of Flumazenil on other anesthetic drugs has been published in the recent studies the mechanism is still unknown. In this case report we present our experience in two patients who unexpectedly recovered from anesthesia following Flumazenil administration. Two male patients respectively at the age of 18 and 19 evaluated as ASA I in preoperative examination, were operated for tonsillectomy, adenoidectomy and septorhinoplasty. One of them was given Midazolam (1 mg iv) as premedication 30 minutes before the operation. Both patients received the same anesthesia induction method (Propofol, Fentanyl) and agents used for maintanence of anesthesia (Sevoflurane, Remifentanil) were identically same. At the end of the operation Atropine and Neostigmine were aplied to the patients to reverse neuromuscular blockers. Signs of recovery from anesthesia were not observed even after more than half an hour period. Flumazenil (0,5 mg iv) were used since there were no any possible reasons to explain this clinical manifestation. In both patients spontaneous eye opening and recovery of respiration were recorded after about a few minutes following Flumazenil administration. Our experience related to these two patients puts forward Flumazenil administration as an unignorable option in delayed recovery from anesthesia and the mechanism behind this phenomenon is worth to proceed further studies.en_US
dc.identifier.endpage106en_US
dc.identifier.issn1300-0578
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84930826539en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage104en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7763
dc.identifier.volume23en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.publisherAnestezi Dergisien_US
dc.relation.ispartofAnestezi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00223
dc.subjectFlumazenilen_US
dc.subjectGeneral anesthesiaen_US
dc.subjectRecoveryen_US
dc.titleDoes Flumazenil effect the anesthetic agents other than benzodiazepines?: Case report [Flumazenil benzodiazepinler dişindaki anestezik ajanlari da etkiler mi?: Olgu sunumu]en_US
dc.typeArticle
dspace.entity.typePublication

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