The effect of smoking on neutrophil/ lymphocyte and platelet/lymphocyte ratio and platelet indices: A retrospective study

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dc.authorid0000-0002-6255-9251en_US
dc.authorid0000-0003-1996-7505en_US
dc.contributor.authorTulgar Y.K.
dc.contributor.authorCakar S.
dc.contributor.authorTulgar S.
dc.contributor.authorDalkilic O.
dc.contributor.authorCakiroglu B.
dc.contributor.authorUyanik B.S.
dc.date.accessioned2024-07-12T21:46:57Z
dc.date.available2024-07-12T21:46:57Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractOBJECTIVE: Smoking commonly leads to death. Although the neutrophil/lymphocyte Ratio, platelet/lymphocyte ratio and platelet indices have been shown to be important for the diagnosis, prognosis and severity of some diseases, the smoking status of patients in these studies has not been well defined. In this study, we compared ratios derived from complete blood count and platelet indices to smoking status and length in smokers and non-smokers. PATIENTS AND METHODS: The data of healthy males and females aged between 18-60 years who presented to our institute for a routine check-up were collected, and subjects were divided in two groups - smokers and non-smokers. The presence of medical history or laboratory results which could affect inflammatory response, formed our exclusion criteria. All complete blood count results were noted and persons' smoking habits were calculated as pack/years. RESULTS: White blood cell, neutrophil, basophil and eosinophil counts; mean corpuscular volume, red cell distribution width and neutrophil/lymphocyte ratio were significantly higher in smokers when compared to non-smokers (p<0.05). When smokers were grouped according to smoking habits; positive linear correlations were detected between pack/year and Neutrophil/lymphocyte ratio and also pack/year and plateletcrit in smokers (p<0.05). CONCLUSIONS: Neutrophil/lymphocyte ratio increases in correlation with pack/year while platelet/lymphocyte ratio is not affected and platelet distribution width is increased in smokers. If smokers are not excluded from studies evaluating neutrophil/lymphocyte ratio and platelet distribution width, the relationship between smoking status as well as pack/year must be determined and reported.en_US
dc.identifier.endpage3118en_US
dc.identifier.issn1128-3602
dc.identifier.issue14en_US
dc.identifier.pmid27460742en_US
dc.identifier.scopus2-s2.0-84990844112en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3112en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7969
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherVerduci Editoreen_US
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00897
dc.subjectLymphocyteen_US
dc.subjectNeutrophilen_US
dc.subjectNeutrophil/lymphocyte ratioen_US
dc.subjectPlateleten_US
dc.subjectPlatelet/lymphocyte ratio.en_US
dc.subjectSmokingen_US
dc.titleThe effect of smoking on neutrophil/ lymphocyte and platelet/lymphocyte ratio and platelet indices: A retrospective studyen_US
dc.typeArticle
dspace.entity.typePublication

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