Comparison of serum androgens and endometrial thickness in obese and non-obese postmenopausal women [Obez ve obez olmayan postmenopozal hastalarda serum androjen seviyeleri ve endometrial kali{dotless}nli{dotless}gn karşi{dotless}laşti{dotless}nlmasi{dotless}]
Küçük Resim Yok
Tarih
2010
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: In this study, we investigated whether serum androgen levels and endometrial thickness differed in obese and non-obese women. Material and Methods: Thirtytwo non-obese (BMI <30) and 48 obese (BMI ? 30) women were enrolled. Blood samples were analyzed for testosterone, free testosterone, androstenedione, DHEAS, and SHBG, and transvaginal ultrasonography was performed. Results: Obese women had significantly higher free testosterone and endometrial thickness and significantly lower SHBG. Eight of 17 women with endometrial thickness >5 mm had significant pathology. Conclusion: These results suggest that obesity may be a risk factor for endometrial carcinoma and other pathologies in post-menopausal women through an action on androgen concentrations.
Açıklama
Anahtar Kelimeler
Endometrial thickness, Obesity, Postmenopause, Serum androgene
Kaynak
Journal of the Turkish German Gynecology Association
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
11
Sayı
3
