Effectiveness of home-based telerehabilitation in mild to moderate Alzheimer's disease: A randomised controlled study
dc.contributor.author | Menengiç, K.N. | |
dc.contributor.author | Yeldan, İ. | |
dc.contributor.author | Çınar, N. | |
dc.contributor.author | Şahiner, T.A. | |
dc.date.accessioned | 2024-07-12T21:40:05Z | |
dc.date.available | 2024-07-12T21:40:05Z | |
dc.date.issued | 2021 | en_US |
dc.department | [Belirlenecek] | en_US |
dc.description.abstract | BACKGROUND: The COVID-19 pandemic has made it necessity that rehabilitation services are provided remotely to patients. These process required a transformation in healthcare. The aim of this study was investigate the effectiveness of the home-based online supervised exercise program in Alzheimer's disease (AD). To our knowledge, this is the first study to report the results of real-time supervised physical exercise telerehabilitation program in AD. METHOD: Eighteen subjects with early-middle stage of AD were randomised into 2 group as telerehabilitation group (TG; mean age: 77.7 ± 5.29 years; 7 Female, 3 Male) and control group (CG; mean age: 78.5 ± 7.07 years; 5 Female, 3 Male). Our primary outcome was Mini-Mental State Examination (MMSE), seconder outcomes were Timed Up&Go (TUG), One-leg Balance Test (OLBT), Functional Independence Measure (FIM), Geriatric Depression Scale-Short Form (GDS). The 6-week motor-cognitive dual-task exercise training was performed online and under the supervision of physiotherapist through videoconference. No physical or cognitive intervention was applied to the control group for 6 weeks. Subjects were assessed before and after the treatment. In statistical analysis, the change in the outcome scores was calculated (? = last measurement-first measurement), the difference between the groups was performed with the Mann Whitney-U Test in SPSS 22.0. Trial's protocol is registered with Clinicaltrials.gov under number NCT04606251. RESULT: There was a significant difference between TG and CG in favor of TG in MMSE, TUG, FIM and GDS (p<0,05); There was no significant difference between groups in OLBT (p>0,05). Statistical results have been showed in Table 1. No safety problem was observed during the treatment. All subjects were completed the study, there was a high adherence to treatment. CONCLUSION: Physical exercise treatment with telerehabilitation was feasible, safe and well-accepted by people with early-middle stage of AD. Online-supervised exercise program can improve cognitive function, functional mobility, independence and reduce depressive symptoms. © 2021 the Alzheimer's Association. | en_US |
dc.identifier.doi | 10.1002/alz.053406 | |
dc.identifier.issn | 1552-5279 | |
dc.identifier.pmid | 34971285 | en_US |
dc.identifier.scopus | 2-s2.0-85123036777 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | e053406 | en_US |
dc.identifier.uri | https://doi.org/10.1002/alz.053406 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12415/7137 | |
dc.identifier.volume | 17 | en_US |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | NLM (Medline) | en_US |
dc.relation.ispartof | Alzheimer's & dementia : the journal of the Alzheimer's Association | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.snmz | KY04924 | |
dc.title | Effectiveness of home-based telerehabilitation in mild to moderate Alzheimer's disease: A randomised controlled study | en_US |
dc.type | Article | |
dspace.entity.type | Publication |