Effectiveness of home-based telerehabilitation in mild to moderate Alzheimer's disease: A randomised controlled study

dc.contributor.authorMenengiç, K.N.
dc.contributor.authorYeldan, İ.
dc.contributor.authorÇınar, N.
dc.contributor.authorŞahiner, T.A.
dc.date.accessioned2024-07-12T21:40:05Z
dc.date.available2024-07-12T21:40:05Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractBACKGROUND: The COVID-19 pandemic has made it necessity that rehabilitation services are provided remotely to patients. These process required a transformation in healthcare. The aim of this study was investigate the effectiveness of the home-based online supervised exercise program in Alzheimer's disease (AD). To our knowledge, this is the first study to report the results of real-time supervised physical exercise telerehabilitation program in AD. METHOD: Eighteen subjects with early-middle stage of AD were randomised into 2 group as telerehabilitation group (TG; mean age: 77.7 ± 5.29 years; 7 Female, 3 Male) and control group (CG; mean age: 78.5 ± 7.07 years; 5 Female, 3 Male). Our primary outcome was Mini-Mental State Examination (MMSE), seconder outcomes were Timed Up&Go (TUG), One-leg Balance Test (OLBT), Functional Independence Measure (FIM), Geriatric Depression Scale-Short Form (GDS). The 6-week motor-cognitive dual-task exercise training was performed online and under the supervision of physiotherapist through videoconference. No physical or cognitive intervention was applied to the control group for 6 weeks. Subjects were assessed before and after the treatment. In statistical analysis, the change in the outcome scores was calculated (? = last measurement-first measurement), the difference between the groups was performed with the Mann Whitney-U Test in SPSS 22.0. Trial's protocol is registered with Clinicaltrials.gov under number NCT04606251. RESULT: There was a significant difference between TG and CG in favor of TG in MMSE, TUG, FIM and GDS (p<0,05); There was no significant difference between groups in OLBT (p>0,05). Statistical results have been showed in Table 1. No safety problem was observed during the treatment. All subjects were completed the study, there was a high adherence to treatment. CONCLUSION: Physical exercise treatment with telerehabilitation was feasible, safe and well-accepted by people with early-middle stage of AD. Online-supervised exercise program can improve cognitive function, functional mobility, independence and reduce depressive symptoms. © 2021 the Alzheimer's Association.en_US
dc.identifier.doi10.1002/alz.053406
dc.identifier.issn1552-5279
dc.identifier.pmid34971285en_US
dc.identifier.scopus2-s2.0-85123036777en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpagee053406en_US
dc.identifier.urihttps://doi.org/10.1002/alz.053406
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7137
dc.identifier.volume17en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherNLM (Medline)en_US
dc.relation.ispartofAlzheimer's & dementia : the journal of the Alzheimer's Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY04924
dc.titleEffectiveness of home-based telerehabilitation in mild to moderate Alzheimer's disease: A randomised controlled studyen_US
dc.typeArticle
dspace.entity.typePublication

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