Periferik arter hastalarının spinal anestezisinde %0.5 bupivacain ve %0.5 Levobupivacain'nin anestezik ve hemodinamik parametreler yönünden karşılaştırılması
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Maltepe Üniversitesi
Erişim Hakkı
Attribution-NonCommercial-NoDerivs 3.0 United States
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada, Kardiyovasküler hastalık potansiyeli taşıyan periferik arter hastalarının spinal anestezisinde %0,5 bupivikain ve %0,5 levobupivakain'in anestezik ve hemodinamik parametreler yönünden karşılaştırılması amaçlandı. Yöntemler: ASA II-III grubu 40 hasta randomize olarak 2 gruba ayrıldı; Grup B'de 3.5 mL %0,5'lik bupivakain, Grup L'de 3.5 mL %0.5'lik levobupivakain intratekal yoldan uygulandı. Sempatik blok soğuk sprey, duyusal blok düzeyi pinprick test ve motor blok derecesi Bromage skala ile değerlendirildi. Motor blok, sempatik blok ve duyusal blok başlama, üst segment yükselme süreleri kaydedildi. Duyusal bloğun en üst segmentten iki segment gerilemesi iki segment gerileme süresi, motor bloğun bir derece azalması bloğun geri dönüş zamanı, Bromega skala 0 motor blok kalkma zamanı olarak kaydedildi. Ortalama arter basıncı (OAB), kalp atım hızı (KAH) ve periferik oksijen satürasyonu (SpO2) değerleri spinal anestezi öncesi ölçülerek başlangıç değerleri olarak kabul edildi ve işlem sonrası 1, 5, 10, 15, 20, 30, 45, ve 60. dakikalarda değerlendirildi. Postoperatif ağrı düzeyleri vizüel anolog skala (VAS) ile değerlendirildi. Bulgular: İstatistiksel Değerlendirmelerde, gruplar arasında demografik özellikler, SpO2, VAS değerleri benzer bulundu. OAB ve KAH'nın; başlangıç değerine göre tüm ölçüm zamanlarında her iki grupta da anlamlı olarak azaldığı, ancak gruplar arasında bir fark olmadığı saptandı (p>0,05). Sempatik, duyusal ve motor blok başlama, üst dermatomlara ulaşma, motor blok gerileme ve motor blok kalkma süreleri iki gruptada benzer bulundu (p>0,05). İki segment gerileme süresi grup B'deki olgularda grup L'e göre ileri düzeyde anlamlı olarak düşük saptandı (p<0,01). Sonuç: Kardiyovasküler hastalık potansiyeli taşıyan periferik arter hastalarında levobupivakain güvenle kullanılabilecek bir lokal anestezik olduğunu kanısına varıldı.
Objective: In this study, it is aimed to compare 0,5% bupivacain and 0,5% levobupivacain in spinal anesthesia for the peripheral arterial disease patients who have a probability of cardiovascular diseases in terms of anesthetic and hemodynamic parameters. Methods: 40 patients in ASA class II or III are randomly separated into 2 groups; in Group B 3,5 ml of bupivacain and in Group L 3,5 ml of levobupivacain have injected intrathecally. Symphatetic blockage is evaluated by cold spray, sensorial blockage is evaluated by pinprick test and the motor blockage is evaluated by Bromage Scale. The beginning and the ascencion to a higher level times of the motor, sympathetic and the sensorial blockages are noted down. 2 levels of regression from the highest level of the sensorial blokcage time is noted as the “2 levels regression time”, 1 grade decrease of the motor blockage time is noted as the “reversion of the motor blockage” and Bromage Scale grade 0 time is noted as the “end of the motor blockage time”. Mean arterial pressure (MAP), heart rate (HR) and peripheral oxygen saturation (SpO2) values are measured before the spinal anesthesia and noted as the beginning values and datas at 1, 5, 10, 15, 20, 30, 45 and 60 minutes after the spinal anesthesia are noted. Postoperative pain levels are evaluated with visual analog scale (VAS). Results: Statistical evaluations of the demographic characteristics, SpO2 and VAS values between the two groups are found similar. MAP and HR are found statistically significantly lower in all of the measurement times in both groups but there is no statistically difference between the two groups (p>0,05). The times of the beginning and the reach to the higher dermatomes of the sympathetic, sensorial and motor blockages, decrease and the end times of the motor blockage are found similar in both groups (p>0,05). 2 levels regression times in Group B are found extremely lower than Grop L (p<0,01). Conclusions: It is convinced that levobupivacain is a local anesthetic substance which is safe to use for the peripheral arterial disease patients who have a probability of cardiovascular diseases.
Objective: In this study, it is aimed to compare 0,5% bupivacain and 0,5% levobupivacain in spinal anesthesia for the peripheral arterial disease patients who have a probability of cardiovascular diseases in terms of anesthetic and hemodynamic parameters. Methods: 40 patients in ASA class II or III are randomly separated into 2 groups; in Group B 3,5 ml of bupivacain and in Group L 3,5 ml of levobupivacain have injected intrathecally. Symphatetic blockage is evaluated by cold spray, sensorial blockage is evaluated by pinprick test and the motor blockage is evaluated by Bromage Scale. The beginning and the ascencion to a higher level times of the motor, sympathetic and the sensorial blockages are noted down. 2 levels of regression from the highest level of the sensorial blokcage time is noted as the “2 levels regression time”, 1 grade decrease of the motor blockage time is noted as the “reversion of the motor blockage” and Bromage Scale grade 0 time is noted as the “end of the motor blockage time”. Mean arterial pressure (MAP), heart rate (HR) and peripheral oxygen saturation (SpO2) values are measured before the spinal anesthesia and noted as the beginning values and datas at 1, 5, 10, 15, 20, 30, 45 and 60 minutes after the spinal anesthesia are noted. Postoperative pain levels are evaluated with visual analog scale (VAS). Results: Statistical evaluations of the demographic characteristics, SpO2 and VAS values between the two groups are found similar. MAP and HR are found statistically significantly lower in all of the measurement times in both groups but there is no statistically difference between the two groups (p>0,05). The times of the beginning and the reach to the higher dermatomes of the sympathetic, sensorial and motor blockages, decrease and the end times of the motor blockage are found similar in both groups (p>0,05). 2 levels regression times in Group B are found extremely lower than Grop L (p<0,01). Conclusions: It is convinced that levobupivacain is a local anesthetic substance which is safe to use for the peripheral arterial disease patients who have a probability of cardiovascular diseases.
Açıklama
Anahtar Kelimeler
bupivikain, levobupivakain, kardiyovasküler hastalık, hemodinami, bupivacain, levobupivacain, cardiovascular disease, hemodynamic
Kaynak
Maltepe Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
1
Künye
Göğebakan, N., Kayacan Örki, T., Güzelmeriç, F., Oğuş, H., Güler, F. ve Koçak, T. (2011). Periferik arter hastalarının spinal anestezisinde %0.5 bupivacain ve %0.5 Levobupivacain'nin anestezik ve hemodinamik parametreler yönünden karşılaştırılması / Comparison of 0,5% bupivacain and 0,5% levobupivacain in terms of anesthetic and hemodynamic parameters in spinal anesthesia for the peripheral artery disease patients. Maltepe Tıp Dergisi. 3(1), s. 10-14.
