A new non-linear optimization of parameters in Michaelis-Menten kinetics

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dc.authorid0000-0001-8357-6694en_US
dc.contributor.authorHeydari, Amir
dc.date.accessioned2024-07-12T20:50:24Z
dc.date.available2024-07-12T20:50:24Z
dc.date.issued2009en_US
dc.departmentFakülteler, İnsan ve Toplum Bilimleri Fakültesi, Matematik Bölümüen_US
dc.description.abstractA new non-linear optimization of parameters in Michaelis-Menten equation has been developed. This method is based on special mathematical form of Michaelis-Menten equation and finding best fitting line of R versus S/ (S +Km). By trying to tend the intercept to zero, the proper Km will be obtained. At the founded Km, the slope is equal to Vm. In this method a non-linear, two-parameter optimization is changed into finding a root of non-linear equation. Generated data set is used to introduce this new method. Data set from literature is used to illustrate accuracy of this technique in comparison with linearization methods. Results show that accuracy of the mentioned method is better than Lineweaver-Burk, Eddie and Hanes methods.en_US
dc.identifier.citationHeydari, A. (2009). A new non-linear optimization of parameters in Michaelis-Menten kinetics. Maltepe Üniversitesi. s. 99.en_US
dc.identifier.endpage100en_US
dc.identifier.isbn9.78605E+12
dc.identifier.startpage99en_US
dc.identifier.urihttps://www.maltepe.edu.tr/Content/Media/CkEditor/03012019014112056-AbstractBookICMS2009Istanbul.pdf#page=76
dc.identifier.urihttps://hdl.handle.net/20.500.12415/2335
dc.institutionauthorHeydari, Amir
dc.language.isoenen_US
dc.publisherMaltepe Üniversitesien_US
dc.relation.ispartofInternational Conference of Mathematical Sciencesen_US
dc.relation.publicationcategoryUluslararası Konferans Öğesi - Başka Kurum Yazarıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY07700
dc.titleA new non-linear optimization of parameters in Michaelis-Menten kineticsen_US
dc.typeConference Object
dspace.entity.typePublication

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