Bir üniversite hastanesinde kandidemi olgularının retreospektif olarak değerlendirilmesi
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Türkiye Tabipleri Birliği
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kandidemi, hastane infeksiyonları arasında sıklığı artan; Candida albicans ve nonalbicans Candida (NAC) türleri ile gelişen ciddi bir infeksiyondur. Çalışmamızda, yatan hastalarda kandidemi etkenlerine göre klinik ve laboratuvar verilerin irdelenmesi amaçlanmıştır. Gereç ve Yöntem: Hastanemiz laboratuvarında 2017-2019 yıllarında kan kültüründe maya üremesi olan 31 hasta retrospektik olarak incelendi. Hastaların klinik ve laboratuvar verileri incelendi. C.albicans ve NAC türü maya üremesine göre gruplar arasında farklılıklar değerlendirildi. Bulgular: Olguların %58’i kadın ve % 52’sinde malignite saptandı. %48’inde kandidemi etkeni olarak C.albicans saptanırken, %52’sinde NAC üredi. Santral venöz kateter varlığı, total parenteral nutrisyon varlığı ve erken üreme oranı (<24 saat) NAC grubunda anlamlı olarak yüksek bulundu. İki grup arasında prokalsitonin, CRP, lökosit, nötrofil, lenfosit, trombosit ve albumin laboratuvar değerleri karşılaştırıldığında anlamlı farklılık saptanmadı. Sonuç: Hastanede yatışı uzamış hastalarda kandidemi önemli bir sorun olmaya devam etmektedir. Risk faktörlerini bilmek ve erken tanı yaklaşımları infeksiyonla mücadelede katkı sağlayacaktır.
Purpose: Candidemia, a serious infection caused by Candida albicans and non-albicans Candida (NAC) species, is an increasing cause of nosocomial infections, We aimed to determine clinical and laboratory features for the patients with candidemia in this study. Materials and Methods: 31 patients with candidemia, between 2017-2019 were retrospectively analyzed. Clinical and laboratory data of the patients were examined. Differences between groups were evaluated according to the growth of C.albicans and NAC. Results: 58% of the cases were women and 52% of the cases had malignancy. C.albicans was detected as the cause of candidemia in 48%, while NAC was produced in 52%. Central venous catheter and total parenteral nutrition and early growth rate (<24 hours) were found to be significantly higher in the NAC group. When the laboratory values of procalcitonin, CRP, leukocyte, neutrophil, lymphocyte, thrombocyte, and albumin were compared between the two groups, no significant difference was found. Conclusion: Candidemia continues to be an important problem in patients with prolonged hospitalization. Identification of risk factors and early diagnosis approaches will lead to better management of preventive and therapeutic measures.
Purpose: Candidemia, a serious infection caused by Candida albicans and non-albicans Candida (NAC) species, is an increasing cause of nosocomial infections, We aimed to determine clinical and laboratory features for the patients with candidemia in this study. Materials and Methods: 31 patients with candidemia, between 2017-2019 were retrospectively analyzed. Clinical and laboratory data of the patients were examined. Differences between groups were evaluated according to the growth of C.albicans and NAC. Results: 58% of the cases were women and 52% of the cases had malignancy. C.albicans was detected as the cause of candidemia in 48%, while NAC was produced in 52%. Central venous catheter and total parenteral nutrition and early growth rate (<24 hours) were found to be significantly higher in the NAC group. When the laboratory values of procalcitonin, CRP, leukocyte, neutrophil, lymphocyte, thrombocyte, and albumin were compared between the two groups, no significant difference was found. Conclusion: Candidemia continues to be an important problem in patients with prolonged hospitalization. Identification of risk factors and early diagnosis approaches will lead to better management of preventive and therapeutic measures.
Açıklama
Anahtar Kelimeler
Kandidemi, Risk faktörleri, Biyokimyasal testler, Candidemia, Risk factors, Biochemical tests
Kaynak
Sürekli Tıp Eğitimi Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
30
Sayı
4
Künye
Karadeniz, A., Öngen İpek, B., Sitar, M.E. ve Hamidi, A.A. (2021). Bir üniversite hastanesinde kandidemi olgularının retreospektif olarak değerlendirilmesi / Retrospective evaluation of candidemia cases in a university hospital evaluation of candidemia cases. Sürekli Tıp Eğitimi Dergisi, Türkiye Tabipleri Birliği. 30(4), s. 252-257.
