Reboxetine may cause amenorrhea in female patients

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dc.authorid0000-0001-5207-6240en_US
dc.authorid0000-0002-1593-2180en_US
dc.contributor.authorYalug, I.
dc.contributor.authorTural, U.
dc.contributor.authorUnsalan, N.
dc.contributor.authorTufan, A. E.
dc.contributor.authorOzten, E.
dc.date.accessioned2024-07-12T21:49:53Z
dc.date.available2024-07-12T21:49:53Z
dc.date.issued2006en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractObjective. Reboxetine is a selective noradrenaline reuptake inhibitor (NaRI), a study on the effects of reboxetine on amenorrhea has not been reported in the literature up to now. This report describes a patient with symptoms of amenorrhea which is thought to be caused by reboxetine. Case. A female patient with major depressive disorder was given reboxetine 8 mg/day. She had experienced secondary amenorrhea for 3 months. The patient had no periodic irregularity before reboxetine use, and after reboxetine was discontinued menstruation resumed. After another trial with reboxetine at the optimal dose (8 mg/day, increased gradually), the patient reported amenorrhea again for 2 months. On discontinuing reboxetine, her menstrual cycle became regular again. Discussion. FSH, LH, E2 and prolactin levels were normal in our patient. Because amenorrhea was temporally related with reboxetine trials, we posit that this phenomenon may be due to side effects of reboxetine. This may be due to noraderenergic effects on hormonal function.en_US
dc.identifier.doi10.1080/13651500600633071
dc.identifier.endpage225en_US
dc.identifier.issn1365-1501
dc.identifier.issn1471-1788
dc.identifier.issue3en_US
dc.identifier.pmid24941062en_US
dc.identifier.scopus2-s2.0-33748463940en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage223en_US
dc.identifier.urihttps://dx.doi.org/10.1080/13651500600633071
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8104
dc.identifier.volume10en_US
dc.identifier.wosWOS:000240109500011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTAYLOR & FRANCIS LTDen_US
dc.relation.ispartofINTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01304
dc.subjectreboxetineen_US
dc.subjectnoradrenalineen_US
dc.subjectprolactinen_US
dc.subjectamenorrheaen_US
dc.subjectdepressionen_US
dc.titleReboxetine may cause amenorrhea in female patientsen_US
dc.typeArticle
dspace.entity.typePublication

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