Immune modulation and its role in antiaging
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springerlink
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Life expectancy of the communities is constantly increasing every minute, including less developed countries. That’s why application of studies to overcome and/or slow aging has always been an important and attractive issue for professional healthcare workers throughout history. There are numerous studies on different theories for explaining the aging process, but none of them can fully explain the cause. As it is known already, aging of different organs differs in a large extent. Fundamentals of this difference are mitotic activity of the tissues and resistance degree to deleterious damages. Cellular and molecular defense mechanisms clearly define resistance degree as “immunity.” Decline in immunity may cause a progressive step in aging. Inflammaging, which is low-grade chronic inflammatory status that is characteristic of the aging process, can be taught to be a biological factor responsible for the age-related diseases in the elderly. Possibility to decrease inflammaging without compromising the physiological role of inflammation can be a strategy for future perspectives. In this chapter we will focus on aging and immune system regulation together with therapies and/or modulations to rehabilitate aging.
Açıklama
Anahtar Kelimeler
Aging, Autoimmunity, Immune modulation, Immunosenescence, Inflammaging
Kaynak
Molecular Basis and Emerging Strategies for Anti-aging Interventions
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Sitar, M.E., Akduman Alaşehir, E. ve Öngen İpek, B. (2018). Immune modulation and its role in antiaging. Rizvi, S. ve Çakatay, U. (Ed.). Molecular Basis and Emerging Strategies for Anti-aging Interventions içinde (ss. 111-132). Berlin: Springer.
