Evaluation of retina nerve fiber layer, ganglion cell-inner plexiform layer and lamina cribrosa in clinically unilateral exfoliative glaucoma

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dc.authorid0000-0001-7749-2814en_US
dc.contributor.authorDemirtas, Atilim Armagan
dc.contributor.authorDuru, Zeynep
dc.contributor.authorDuru, Necati
dc.contributor.authorErdogan, Hakika
dc.date.accessioned2024-07-12T21:43:24Z
dc.date.available2024-07-12T21:43:24Z
dc.date.issued2020en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractPurpose To compare retinal nerve fiber layer (RNFL), ganglion cell-inner plexiform layer (GC-IPL), the lamina cribrosa depth (LCD) and thickness (LCT) in unilateral exfoliative glaucoma (EXG) patients with their fellow eyes without exfoliation and control eyes. Methods This cross-sectional prospective single-center study consisted of 64 eyes of 32 patients with unilateral EXG and 35 eyes of controls. All subjects were examined with spectral domain optical coherence tomography for the RNFL and GC-IPL measurements. The LCD and LCT measurements were also obtained. Results The RNFL measurements at all quadrants were statistically thinner in EXG eyes than those in their eyes without EXG and control eyes (p < 0.001 for average, superior, temporal and inferior; p = 0.004 for nasal). The EXG group had deeper LCD than their eyes without EXG and control eyes (p < 0.001, for both). The fellow eyes of EXG group had also deeper LCD than control eyes, with no statistical significance (p = 0.058). The mean LCT was thinner in EXG eyes compared to those in the eyes without EXG and control eyes (p < 0.001, for both). The eyes without EXG and control eyes had similar LCT (p = 0.293). Conclusions Recent developments in imaging technology give the clinician detailed structural information about optic nerve head and retina such as GC-IPL, LCD and LCT. In addition to follow-up of RNFL changes, these new parameters may be useful in recognizing progression in EXG patients.en_US
dc.identifier.citationDemirtas, AA., Duru, Z., Duru, N. ve Erdogan, H. (2020). Evaluation of retina nerve fiber layer, ganglion cell-inner plexiform layer and lamina cribrosa in clinically unilateral exfoliative glaucoma. SPRINGER. 40(10), s. 2691-2697.en_US
dc.identifier.doi10.1007/s10792-020-01452-y
dc.identifier.endpage2697en_US
dc.identifier.issn1573-2630
dc.identifier.issue10en_US
dc.identifier.pmid32476077en_US
dc.identifier.scopus2-s2.0-85085577450en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2691en_US
dc.identifier.urihttps://doi.prg/10.1007/s10792-020-01452-y
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7596
dc.identifier.volume40en_US
dc.identifier.wosWOS:000538442800001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofINTERNATIONAL OPHTHALMOLOGYen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01310
dc.subjectExfoliative glaucomaen_US
dc.subjectLamina cribrosa depthen_US
dc.subjectGanglion cell complexen_US
dc.subjectRetina nerve fiber layeren_US
dc.subjectLamina cribrosa thicknessen_US
dc.titleEvaluation of retina nerve fiber layer, ganglion cell-inner plexiform layer and lamina cribrosa in clinically unilateral exfoliative glaucomaen_US
dc.typeArticle
dspace.entity.typePublication

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