Macula and Retinal Nerve Fiber Layer in Migraine Patients: Analysis By Spectral Domain Optic Coherence Tomography

dc.authorid0000-0003-1657-9099en_US
dc.contributor.authorYulek, Fatma
dc.contributor.authorDirik, Ebru Bilge
dc.contributor.authorEren, Yasemin
dc.contributor.authorSimavli, Huseyin
dc.contributor.authorUgurlu, Nagihan
dc.contributor.authorCagIl, Nurullah
dc.contributor.authorSimsek, Saban
dc.date.accessioned2024-07-12T21:53:21Z
dc.date.available2024-07-12T21:53:21Z
dc.date.issued2015en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractAim: Investigating the retinal nerve fiber layer (RNFL), macular and ganglion cell complex thickness in eyes of migraine patients using optical coherence tomography. Methods: The study was designed as an observational cross-sectional study. 50 patients with migraine (30 patients with aura and 20 patients without aura) and 50 healthy volunteers were included. Optical coherence tomography was performed with Optovue technology. The fast RNFL thickness (3.4) scan, MM5, and GCC acquisition protocols were used. Results: There was no statistically significant difference in retinal thickness in any of the quadrants between the control group and the migraine patients (p>0.05). The average RNFL thickness (110.50 vs 102.84 microns, p = 0.03) was significantly thinner in migrainers as compared to the control. The ANOVA did not reveal any significant difference between migrainers with aura, migrainers without aura, and the control group. The VAS (visual analogue scale) score of migraine patients was not statistically significantly correlated with any of the parameters, while the length of migraine history was negatively correlated with the average RNFL thickness (r = -0.32, p = 0.03). Conclusion: The average RNFL thickness in the migraine patients was found to be thinner than that in the control group. In addition, we found a negative weak correlation between length of migraine history and the average RNFL thickness, supporting the possible association between these pathologies.en_US
dc.identifier.doi10.3109/08820538.2013.833270
dc.identifier.endpage128en_US
dc.identifier.issn0882-0538
dc.identifier.issn1744-5205
dc.identifier.issue2en_US
dc.identifier.pmid24171810en_US
dc.identifier.scopus2-s2.0-84924073808en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage124en_US
dc.identifier.urihttps://dx.doi.org/10.3109/08820538.2013.833270
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8482
dc.identifier.volume30en_US
dc.identifier.wosWOS:000350451500007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherINFORMA HEALTHCAREen_US
dc.relation.ispartofSEMINARS IN OPHTHALMOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY03409
dc.subjectGanglion cell complex thicknessen_US
dc.subjectmacular thicknessen_US
dc.subjectmigraineen_US
dc.subjectnerve fiber layer thicknessen_US
dc.subjectspectral domain optical coherence tomographyen_US
dc.titleMacula and Retinal Nerve Fiber Layer in Migraine Patients: Analysis By Spectral Domain Optic Coherence Tomographyen_US
dc.typeArticle
dspace.entity.typePublication

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