Clinical Determinants of Cognitive Dysfunctions and Cognitive Endophenotypes in Bipolar Disorder
Küçük Resim Yok
Tarih
2010
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Yerkure Tanitim & Yayincilik Hizmetleri A S
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Verbal learning, verbal memory and executive functions foremost, working memory, (sustained) attention and processing speed are substantial cognitive domains in bipolar disorder. Dysfuntions in verbal learning and memory might be observed in first degree relatives as well; and thus seem to be best candidates for the cognitive endophenotype concept. Prior psychotic episodes, numbers and types of episodes, age of illness onset and duration of illness are clinical parameters seem to influence cognitive functions. There are relatively limited numbers of researches about cognitive dysfunctions in early onset forms, old age, type II disorder and comorbidity aspects of bipolar disorders. Results from the researches regarding qualitative and quantitative effects of medications on cognition are inconsistent. Cognitive deficits of first degree relatives and familial resemblance of deficits might be indicators of heritability of cognitive functions, therefore taking genetic models into account in designs of researches may provide considerable data.
Açıklama
Anahtar Kelimeler
Bipolar Disorder, Cognitive Dysfunctions, Endophenotype, Clinic Determinents
Kaynak
Dusunen Adam-Journal of Psychiatry And Neurological Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
23
Sayı
4
