Clinical Determinants of Cognitive Dysfunctions and Cognitive Endophenotypes in Bipolar Disorder

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dc.contributor.authorAtagn, Murat İlhan
dc.contributor.authorBalaban, Özlem Devrim
dc.contributor.authorAltınbas, Kursat
dc.contributor.authorYesilyurt, Sema
dc.contributor.authorTan, Devran
dc.date.accessioned2024-07-12T21:40:53Z
dc.date.available2024-07-12T21:40:53Z
dc.date.issued2010en_US
dc.department[Belirlenecek]en_US
dc.description.abstractVerbal learning, verbal memory and executive functions foremost, working memory, (sustained) attention and processing speed are substantial cognitive domains in bipolar disorder. Dysfuntions in verbal learning and memory might be observed in first degree relatives as well; and thus seem to be best candidates for the cognitive endophenotype concept. Prior psychotic episodes, numbers and types of episodes, age of illness onset and duration of illness are clinical parameters seem to influence cognitive functions. There are relatively limited numbers of researches about cognitive dysfunctions in early onset forms, old age, type II disorder and comorbidity aspects of bipolar disorders. Results from the researches regarding qualitative and quantitative effects of medications on cognition are inconsistent. Cognitive deficits of first degree relatives and familial resemblance of deficits might be indicators of heritability of cognitive functions, therefore taking genetic models into account in designs of researches may provide considerable data.en_US
dc.identifier.doi10.5350/DAJPN2010230407
dc.identifier.endpage274en_US
dc.identifier.issn1018-8681
dc.identifier.issn1309-5749
dc.identifier.issue4en_US
dc.identifier.startpage265en_US
dc.identifier.urihttps://doi.org/10.5350/DAJPN2010230407
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7541
dc.identifier.volume23en_US
dc.identifier.wosWOS:000421417700009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherYerkure Tanitim & Yayincilik Hizmetleri A Sen_US
dc.relation.ispartofDusunen Adam-Journal of Psychiatry And Neurological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY09382
dc.subjectBipolar Disorderen_US
dc.subjectCognitive Dysfunctionsen_US
dc.subjectEndophenotypeen_US
dc.subjectClinic Determinentsen_US
dc.titleClinical Determinants of Cognitive Dysfunctions and Cognitive Endophenotypes in Bipolar Disorderen_US
dc.typeReview Article
dspace.entity.typePublication

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