Comparison of intra-articular bupivacaine-morphine with bupivacaine-tenoxicam combinations on post-operative analgesia in patients with arthroscopic meniscectomy: a prospective, randomised study

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dc.authorid0000-0002-2469-7231en_US
dc.authorid0000-0003-1829-5700en_US
dc.contributor.authorSanel, Selim
dc.contributor.authorArpaz, Osman
dc.contributor.authorUnay, Koray
dc.contributor.authorTurkmen, Ismail
dc.contributor.authorSimsek, Selcuk
dc.contributor.authorUgutmen, Ender
dc.date.accessioned2024-07-12T21:43:30Z
dc.date.available2024-07-12T21:43:30Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractAim There are many alternatives for post-operative pain relief in patients who have had general anaesthesia. The aim of this study was to evaluate the efficacy of intra-articular bupivacaine + morphine and bupivacaine + tenoxicam applications in post-operative pain control in patients undergoing knee arthroscopy with general anaesthesia. Method This was a prospective study. Standard anaesthesia procedures were applied to each patient, and the 240 patients chosen at random were then divided into two groups. Each group received a different combination of drugs for this double-blind study. The first group (group A: 120 patients) received 0.5 % bupivacaine 100 mg + tenoxicam 20 mg (22 ml); the second group (group B) received 0.5 % bupivacaine 100 mg + morphine 2 mg (22 ml); both groups received their drugs at the end of the intra-articular operation before tourniquet deflation. Before the operation, patients were asked about their post-operative pain at particular periods over the following 24 hours using the visual analogue scale (VAS) and the numeric rating scale (NRS). An additional analgaesic requirement and possible side effects were also recorded. Results Group A patients needed analgaesics sooner after operation than patients in group B. In Group B, VAS and NRS values were statistically higher compared with group A at the 12th hour. There were also fewer side effects seen in group A versus group B. Conclusion Effective and reliable results were obtained in post-operative pain control in bupivacaine added to the morphine or tenoxicam groups following arthroscopic meniscectomy. In the tenoxicam group, patients reported less pain, fewer side effects and less need for analgesics at 12 hours after the operation.en_US
dc.identifier.doi10.1007/s00264-015-2990-5
dc.identifier.endpage605en_US
dc.identifier.issn0341-2695
dc.identifier.issn1432-5195
dc.identifier.issue3en_US
dc.identifier.pmid26374114en_US
dc.identifier.scopus2-s2.0-84958851521en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage601en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s00264-015-2990-5
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7610
dc.identifier.volume40en_US
dc.identifier.wosWOS:000371084600025en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSPRINGERen_US
dc.relation.ispartofINTERNATIONAL ORTHOPAEDICSen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01311
dc.subjectAnalgesiaen_US
dc.subjectBupivacaineen_US
dc.subjectIntra-articularen_US
dc.subjectMeniscectomyen_US
dc.subjectMorphineen_US
dc.subjectTenoxicamen_US
dc.titleComparison of intra-articular bupivacaine-morphine with bupivacaine-tenoxicam combinations on post-operative analgesia in patients with arthroscopic meniscectomy: a prospective, randomised studyen_US
dc.typeArticle
dspace.entity.typePublication

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