Mean platelet volume in Behçet's disease

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dc.authorid0000-0002-4936-3705en_US
dc.contributor.authorKarabudak, Özlem
dc.contributor.authorNalbant, Selim
dc.contributor.authorŞahan, Burak
dc.contributor.authorÜnal, Melih
dc.contributor.authorErşanlı, Dilaver
dc.date.accessioned2024-07-12T21:01:23Z
dc.date.available2024-07-12T21:01:23Z
dc.date.issued2008en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: Determination of mean platelet volume (MPV) is a very simple and cheap method to measure platelet activation; it has been shown to increase in cases of ischemic vascular events. Objective: The aim of this study was to evaluate platelet activation status by using MPV in patients with Behçet's disease (BD) and to search for a possible relationship between platelet function and disease activity. Patients and Methods: We selected 58 consecutive patients with BD. The control group consisted of 30 healthy subjects. BD patients were classified as active and inactive, according to clinical findings and severity criteria. MPV was determined in a blood sample collected in citrate. The groups were compared using Student's t test. Results:There was no significant difference between BD and control groups with regard to the platelet and white blood cell (WBC) counts. There was a tendency for higher MPV in BD patients when compared with the healthy subjects. However, the difference was not statistically significant (p = 0.1). When the patients with active BD and inactive BD were compared, there was no statistically significant difference with respect to MPV (p = 0.8). Conclusion: Even if the platelet activation status determined by using MPV in BD did not show a statistical correlation with healthy controls, we did detect higher MPV values ??in BD patients. In addition ESR and CRP showed statistical correlations which may suggest a possible relation of platelet functions with disease activity.en_US
dc.identifier.citationKarabudak, Ö., Nalbant, S., Şahan, B., Ünal, M. ve Erşanlı, D. (2008). Mean platelet volume in Behçet's disease. Aktuelle Rheumatologie, Thieme Medical Publishers. 33(4), 217-220.en_US
dc.identifier.endpage220en_US
dc.identifier.issn0341-051X
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2008-1027205
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3498
dc.identifier.volume33en_US
dc.language.isoenen_US
dc.publisherThieme Medical Publishersen_US
dc.relation.ispartofAktuelle Rheumatologieen_US
dc.relation.isversionof10.1055 / s-2008-1027205en_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00154
dc.subjectMean platelet volumeen_US
dc.subjectM. Behçeten_US
dc.titleMean platelet volume in Behçet's diseaseen_US
dc.typeArticle
dspace.entity.typePublication

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