The effect of PCOS status on atherosclerosis markers and cardiovascular disease risk factors in young women with vitamin D deficiency

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dc.contributor.authorAtasayan, Kemal
dc.contributor.authorYoldemir, Tevfik
dc.date.accessioned2024-07-12T21:43:23Z
dc.date.available2024-07-12T21:43:23Z
dc.date.issued2020en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractObjective To investigate whether polycystic ovary syndrome (PCOS) had further deteriorating influence on endothelial function or cardiometabolic parameters in women with vitamin D deficiency during reproductive age. Study design The study group was composed of women with PCOS and vitamin D deficiency and insufficiency between the ages of 18 and 35 years. Age and body mass index (BMI)-matched women were chosen as controls. Serum 25(OH) Vit D levels below 20 ng/mL were considered as vitamin D deficiency. The cutoff level of vitamin D insufficiency was suggested at 30 ng/mL. Serum FSH, LH, estradiol, testosterone, DHEA-S, fasting glucose, total cholesterol, HDL, LDL, triglyceride levels were analyzed. Carotid artery intima-media thickness (CIMT) was measured, and the flow-mediated vasodilation (FMD) was calculated. Results CIMT and FMD values in both vitamin D deficiency and insufficiency subgroups showed no significant difference between PCOS and non-PCOS groups. There was a weak negative correlation between BMI, waist/hip ratio, CRP, and 25(OH) Vitamin D. Conclusion PCOS is a heterogeneous disease with different combinations of the diagnostic components. Vitamin D is an important variable for a healthy cardiovascular system. We did not find any difference in early atherosclerotic markers and cardiometabolic features between PCOS and non-PCOS group with Vitamin D deficiency.en_US
dc.identifier.citationAtasayan, K. ve Yoldemir, T. (2020). The effect of PCOS status on atherosclerosis markers and cardiovascular disease risk factors in young women with vitamin D deficiency. Gynecological Endocrinology, Taylor & Francis.en_US
dc.identifier.doi10.1080/09513590.2020.1826428
dc.identifier.issn1473-0766
dc.identifier.pmid32996333en_US
dc.identifier.scopus2-s2.0-85091877538en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/09513590.2020.1826428
dc.identifier.urihttps://doi.prg/10.1080/09513590.2020.1826428
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7594
dc.identifier.wosWOS:000573983100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY01110
dc.subjectPCOSen_US
dc.subjectvitamin D deficiencyen_US
dc.subjectvitamin D insufficiencyen_US
dc.subjectCIMTen_US
dc.subjectFMDen_US
dc.titleThe effect of PCOS status on atherosclerosis markers and cardiovascular disease risk factors in young women with vitamin D deficiencyen_US
dc.typeArticle
dspace.entity.typePublication

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