Effect of a bovine collagen matrix on tendon adhesions during the repair of rat Achilles tendon

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dc.authoridToksöz Yıldırım, Ayşe Nur/0000-0003-1708-0003en_US
dc.authoridToksöz Yıldırım, Ayşe Nur/0000-0003-1708-0003en_US
dc.authoridBozdag, Ergun/0000-0001-7412-1129en_US
dc.authoridYAMAK, Fatih/0000-0002-1927-2802en_US
dc.authoridYAMAK, Fatih/0000-0002-1927-2802en_US
dc.authoridGurler, Mehmet/0000-0001-8470-9276en_US
dc.contributor.authorGürler, M.
dc.contributor.authorAksan, T.
dc.contributor.authorÖzturk, M. B.
dc.contributor.authorTezcan, M.
dc.contributor.authorYıldırım, A. N. Toksöz
dc.contributor.authorBozdag, E.
dc.contributor.authorAltıner, N.
dc.date.accessioned2024-07-12T21:37:57Z
dc.date.available2024-07-12T21:37:57Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractAdhesion after a tendon injury is one of the major problems following upper extremity surgery. In the present study, we evaluated a new material that is clinically usable as an adhesion barrier. Twenty-four male Wistar albino rats were used in the study. These rats (48 legs) were divided into three groups: sham, control, and experimental. No surgical intervention was performed in the sham group. After making a full-thickness cut through the right Achilles tendon, the tendon was repaired using the modified Kessler technique in the control group, while bovine collagen matrix was wrapped around the surgically repaired tendon using the modified Kessler technique in the experimental group. Two months after surgery, the operated and non-operated tendons were resected and analyzed through biomechanical, macroscopic, and histopathological examinations. The results of the biomechanical testing did not differ significantly between the control and experimental groups. Macroscopic examination of the adhesions revealed less adhesions in the experimental group but this difference was not statistically significant. Moreover, the results of the histopathological examination, which was performed based on five criteria, did not differ significantly between the two groups. Our study's results indicate that a bovine collagen matrix can be used to prevent tendon adhesion; however, larger studies are needed to verify these findings. (C) 2021 SFCM. Published by Elsevier Masson SAS. All rights reserved.en_US
dc.identifier.doi10.1016/j.hansur.2021.01.005
dc.identifier.endpage257en_US
dc.identifier.issn2468-1229
dc.identifier.issn2468-1210
dc.identifier.issue3en_US
dc.identifier.pmid33667653en_US
dc.identifier.scopus2-s2.0-85103414855en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage250en_US
dc.identifier.urihttps://doi.org/10.1016/j.hansur.2021.01.005
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6988
dc.identifier.volume40en_US
dc.identifier.wosWOS:000651466700006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofHand Surgery & Rehabilitationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY04330
dc.subjectTendon Adhesionen_US
dc.subjectRaten_US
dc.subjectAchilles Tendonen_US
dc.subjectTendon Repairen_US
dc.subjectBovine Collagen Matrixen_US
dc.titleEffect of a bovine collagen matrix on tendon adhesions during the repair of rat Achilles tendonen_US
dc.typeArticle
dspace.entity.typePublication

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