Analysis of obstructive sleep apnea patients with "sawtooth sign" on the flow-volume curve

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dc.authorid0000-0001-7360-8269en_US
dc.authorid0000-0003-3311-3338en_US
dc.contributor.authorLevent, Ender
dc.contributor.authorSariman, Nesrin
dc.date.accessioned2024-07-12T21:53:23Z
dc.date.available2024-07-12T21:53:23Z
dc.date.issued2011en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractThe aims of the present study are to determine whether there is an obstructive sleep apnea (OSA) subgroup presenting with sawtooth sign on the spirometric flow-volume curve, and to identify the clinical importance of the sawtooth sign in these patients. The study subjects consisted of 134 OSA patients (a parts per thousand yen18 years) whose spirometric tests were made on the same day with the polysomnography. Patients without sawtooth sign were taken as the control group. Patients with sawtooth sign and control subjects were retrospectively analyzed in terms of distinctive demographic, anthropometric, polysomnographic, and spirometric characteristics. OSA patients with sawtooth sign (n = 36) had greater neck circumference and body weight, and were taller than control subjects (n = 98). Patients with sawtooth sign were mainly males (p < 0.01). Female/male ratios were similar in control subjects. The presence of coronary artery disease was higher (p = 0.024), and current smokers were more (p = 0.014) among the patients with sawtooth sign than control subjects. In logistic regression analysis, the presence of sawtooth sign and age were the only statistically significant parameters (p = 0.028 and p = 0.002, respectively) that affect the likelihood of coronary artery diseases. There were no differences among the groups with regard to age, BMI, wrist circumference, and other comorbid conditions. The duration time of oxygen desaturation (< 90%), avarage, and longest duration of total apnea were longer (p = 0.050, p = 0.034 and p = 0.014, respectively) and the obstructive apnea index was more (p = 0.035) in OSA patients with sawtooth sign when compared to control subjects. There were no differences with regard to other polysomnographic parameters, sleep architecture, Epworth sleepiness score, and spirometric parameters. As an OSA subgroup, the OSA patients with sawtooth sign may have more frequent and longer duration of obstructive apneas, longer duration time of oxygen desaturation, and greater risk for the coronary artery disease.en_US
dc.identifier.doi10.1007/s11325-010-0393-9
dc.identifier.endpage365en_US
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.issue3en_US
dc.identifier.pmid20661653en_US
dc.identifier.scopus2-s2.0-80054884025en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage357en_US
dc.identifier.urihttps://dx.doi.org/10.1007/s11325-010-0393-9
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8490
dc.identifier.volume15en_US
dc.identifier.wosWOS:000295529600013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSPRINGER HEIDELBERGen_US
dc.relation.ispartofSLEEP AND BREATHINGen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY03426
dc.subjectObstructive sleep apneaen_US
dc.subjectSawtooth signen_US
dc.subjectFlow-volume curveen_US
dc.subjectSpirometryen_US
dc.subjectCoronary artery diseaseen_US
dc.titleAnalysis of obstructive sleep apnea patients with "sawtooth sign" on the flow-volume curveen_US
dc.typeArticle
dspace.entity.typePublication

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