Western Diet and Cognitive Impairment: Links to Potential Mechanisms: A Review
| dc.contributor.author | Aslan, B. | |
| dc.date.accessioned | 2024-07-12T21:40:55Z | |
| dc.date.available | 2024-07-12T21:40:55Z | |
| dc.date.issued | 2023 | en_US |
| dc.department | [Belirlenecek] | en_US |
| dc.description.abstract | Animal studies in recent years have shown that a Western diet style (WD-style) which is high in saturated fat and refined carbohydrates causes obesity, metabolic syndrome and cardiovascular diseases. In addition, results demonstrated that it can damage the structures that make up the nervous system. Accordingly, there is an evidence that systemic changes associated with the Western diet lead to blood-brain barrier (BBB) disruption, microglia activation, and the development of neuroinflammation. These changes are then followed by synaptic transmission dysfunction, neurodegeneration, and finally memory and cognitive deterioration. This review summarizes research on the mechanisms that show Western diet consumption is associated with cognitive impairment, with emphasis on learning and memory functions that depend on the integrity of the hippocampus. © 2023, Shiraz University of Medical Sciences. All rights reserved. | en_US |
| dc.identifier.doi | 10.30476/ijns.2023.98726.1234 | |
| dc.identifier.endpage | 143 | en_US |
| dc.identifier.issn | 2538-1873 | |
| dc.identifier.issue | 3 | en_US |
| dc.identifier.scopus | 2-s2.0-85173450307 | en_US |
| dc.identifier.scopusquality | N/A | en_US |
| dc.identifier.startpage | 131 | en_US |
| dc.identifier.uri | https://doi.org/10.30476/ijns.2023.98726.1234 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12415/7554 | |
| dc.identifier.volume | 8 | en_US |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | en_US |
| dc.publisher | Shiraz University of Medical Sciences | en_US |
| dc.relation.ispartof | International Journal of Nutrition Sciences | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.snmz | KY09428 | |
| dc.subject | Cognitive Functions | en_US |
| dc.subject | Learning | en_US |
| dc.subject | Memory | en_US |
| dc.subject | Neuroinflammation | en_US |
| dc.subject | Western Diet | en_US |
| dc.title | Western Diet and Cognitive Impairment: Links to Potential Mechanisms: A Review | en_US |
| dc.type | Review Article | |
| dspace.entity.type | Publication |
