Determination of Dichlorvos Effect on Uterine Contractility Using Wavelet Transform
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Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
ELSEVIER SCIENCE INC
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Purpose: The use of organic synthetic pesticides has increased heavily in recent years and organophosphate insecticides constitute 20-38% of the total pesticides used worldwide. Dichlorvos, an organic phosphate insecticide, is widely used for the control of the agricultural, industrial and domestic pest in most of the agricultural countries like Turkey and it is known that many chemical toxins are capable of producing changes in uterine contractions. In this study, the effects of different doses of dichlorvos on isolated uterus muscle contractions are evaluated. Methods: Wavelet scalogram analysis is preferred in the study because of its simultaneous time, frequency and energy screening capability. Results: Obtained results show that 50 mu M and 100 mu M doses of DDVP significantly decreased the energy of contractions. Conclusions: The study is important in that it shows toxic effects of DDVP on uterus which is responsible for reproductive function of mammalians and that it draws attention to an important public health problem. Furthermore, this is the first study showing that the wavelet transform can be readily utilized to determine the effects of insecticides and similar chemicals on the uterus spontaneous activity. (C) 2016 AGBM. Published by Elsevier Masson SAS. All rights reserved.
Description
Keywords
Dichlorvos, Uterus, Wavelet scalogram, Spontaneous activity, Contraction
Journal or Series
IRBM
WoS Q Value
Q4
Scopus Q Value
Q2
Volume
37
Issue
05.Jun
