Comparison of diclofenac sodium with indomethacin suppositories for mediolateral episiotomies

dc.contributor.authorAltungül A.Ç.
dc.contributor.authorSapmaz E.
dc.contributor.authorKale A.
dc.date.accessioned2024-07-12T21:45:53Z
dc.date.available2024-07-12T21:45:53Z
dc.date.issued2012en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractObjective: The study was carried out to compare the analgesic effect of diclofenac sodium and indomethacin suppositories for management of right mediolateral episiotomy repair. Method: A total of 70 patients who gave birth vaginally with right mediolateral episitomy were randomly assigned to receive 100 mg diclofenac sodium suppositories/day (G1, n = 35) or 100 mg indomethacin supposotories/day (G2, n = 35) after episiotomy repair and postpartum for three days. Pain ratings were recorded before, the first hour and 24 hours after medication. The verbal rating scale (VRS) and visual analog scale (VAS) were used for pain recording. The independent T test, Mann-Whitney U and Wilcoxon rank test were used for statistical analysis and Spearman correlation analysis was used for comparison between VRS and VAS. Results: Diclofenac sodium was a more effective analgesic than indomethacin suppositories for right mediolateral episiotomy pain. For G1 the first hour VRS was 2.6 ± 0.5 points and VAS 4.9 ± 0.8 points; for G2 the first hour VRS was 3.4 ± 0.6 points VAS 6.6 ± 1.2 points; this difference was statistically significant (p < 0.05, Mann-Whitney U test). For Gl at the 24 th hour VRS was 1.2 ± 0.4 points and VAS 2.4 ± 0.9 points; for G2 at the 24 th hour VRS was 2 ± 0.7 points and VAS was 3.4 ± 1.3 points; the difference was statistically significant (p < 0.05, Mann-Whitney U test). The first and 24 th hour pain scores (VAS1-VAS24, VRS1-VRS24) were decreased dramatically for both groups (p < 0.05, Wilcoxon rank test). A positive correlation was obtained between the first and 24 th hour VRS and VAS by Spearman correlation analysis (r s = 0.9, n = 70, p = 0.000). Conclusion: The two analgesics were effective after episiotomy repair, however diclofenac sodium suppositories may be the preferred choice because they were more effective.en_US
dc.identifier.endpage114en_US
dc.identifier.issn0390-6663
dc.identifier.issue1en_US
dc.identifier.pmid22675968en_US
dc.identifier.scopus2-s2.0-84860862459en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage112en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7862
dc.identifier.volume39en_US
dc.identifier.wosWOS:000301509900025en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofClinical and Experimental Obstetrics and Gynecologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00526
dc.subjectDiclofenac sodiumen_US
dc.subjectIndomethacinen_US
dc.subjectMediolateral episiotomyen_US
dc.subjectPainen_US
dc.titleComparison of diclofenac sodium with indomethacin suppositories for mediolateral episiotomiesen_US
dc.typeArticle
dspace.entity.typePublication

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