Anticancer properties of astaxanthin: A molecule of great promise
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Astaxanthin (ATX) is a lipid-soluble xanthophyll carotenoid naturally found in a variety of microorganisms, such as yeast and microalgae, and marine animals including shrimp, salmon, lobster, and clamp. ATX is the most powerful antioxidant among carotenoids mainly due to its unique molecular structure and interaction with the cell membrane. Several studies conducted in in vitro and in vivo models revealed the beneficial health effects of ATX mostly attributed to its outstanding antioxidant activity. ATX has been reported to have important biological activities against a number of pathophysiological conditions including inflammation, diabetes, cardiovascular diseases, and aging. Significant anticancer activities have also been reported for ATX in various types of cancer including breast, colon, oral, lung, bladder, gastric, esophageal as well as melanoma, leukemia, and hepatocellular carcinoma. This chapter focuses on the potential mechanisms of cancer preventive effects of ATX, inhibitory effects of ATX on the processes involved in malignant transformation, and the use of ATX in combination with anticancer drugs. © 2021 Elsevier Inc.
Açıklama
Anahtar Kelimeler
Anticancer Properties, Antiinflammatory Activity, Antioxidant Activity, Apoptosis, Astaxanthin, Combination Cancer Treatment, Immunomodulatory Activity, Invasion, Metastasis, Proliferation
Kaynak
Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications
WoS Q Değeri
Scopus Q Değeri
N/A
