Anticancer properties of astaxanthin: A molecule of great promise

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dc.contributor.authorDemirel, P.B.
dc.contributor.authorTuna, B.G.
dc.date.accessioned2024-07-12T21:40:28Z
dc.date.available2024-07-12T21:40:28Z
dc.date.issued2021en_US
dc.department[Belirlenecek]en_US
dc.description.abstractAstaxanthin (ATX) is a lipid-soluble xanthophyll carotenoid naturally found in a variety of microorganisms, such as yeast and microalgae, and marine animals including shrimp, salmon, lobster, and clamp. ATX is the most powerful antioxidant among carotenoids mainly due to its unique molecular structure and interaction with the cell membrane. Several studies conducted in in vitro and in vivo models revealed the beneficial health effects of ATX mostly attributed to its outstanding antioxidant activity. ATX has been reported to have important biological activities against a number of pathophysiological conditions including inflammation, diabetes, cardiovascular diseases, and aging. Significant anticancer activities have also been reported for ATX in various types of cancer including breast, colon, oral, lung, bladder, gastric, esophageal as well as melanoma, leukemia, and hepatocellular carcinoma. This chapter focuses on the potential mechanisms of cancer preventive effects of ATX, inhibitory effects of ATX on the processes involved in malignant transformation, and the use of ATX in combination with anticancer drugs. © 2021 Elsevier Inc.en_US
dc.identifier.doi10.1016/B978-0-12-823304-7.00003-9
dc.identifier.endpage445en_US
dc.identifier.isbn9.78013E+12
dc.identifier.scopus2-s2.0-85113575544en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage427en_US
dc.identifier.urihttps://doi.org/10.1016/B978-0-12-823304-7.00003-9
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7301
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofGlobal Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applicationsen_US
dc.relation.publicationcategoryKitap Bölümü - Uluslararasıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY05387
dc.subjectAnticancer Propertiesen_US
dc.subjectAntiinflammatory Activityen_US
dc.subjectAntioxidant Activityen_US
dc.subjectApoptosisen_US
dc.subjectAstaxanthinen_US
dc.subjectCombination Cancer Treatmenten_US
dc.subjectImmunomodulatory Activityen_US
dc.subjectInvasionen_US
dc.subjectMetastasisen_US
dc.subjectProliferationen_US
dc.titleAnticancer properties of astaxanthin: A molecule of great promiseen_US
dc.typeBook Chapter
dspace.entity.typePublication

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