Do early procalcitonine levels aid in predicting mortality in burn patients?

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dc.authorid0000-0003-1996-7505en_US
dc.authorid0000-0002-8278-5934en_US
dc.contributor.authorPiroglu I.D.
dc.contributor.authorTulgar S.
dc.contributor.authorPiroglu M.D.
dc.contributor.authorThomas D.T.
dc.contributor.authorKarakilic E.
dc.contributor.authorGergerli R.
dc.contributor.authorAtes N.G.
dc.contributor.authorDemir A.
dc.date.accessioned2024-07-12T21:49:57Z
dc.date.available2024-07-12T21:49:57Z
dc.date.issued2016en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractAim: Burn patients in intensive care units (ICU) are at high risk of mortality. Our aim in this stuy is to evaluate the use of first 48 hour procalcitonin level (PCT), C-reactive protein (CRP) and APACHE II score for the prediction of mortality in burn patients admitted to ICU. Material and method: Files of patients with burns admitted to a tertiary centre’s burn unit were retrospectively analysed and those with procalcitonin and C-reactive protein level measurements and APACHE II scores within first 48 hours of admittance were included in this study. Patients with comorbidities that would effect PCT and CRP levels such as chronic renal or liver failure were excluded from the study. Patients PCT, CRP and APACHE II scores were compared with the outcome of patients. Results: Seventy patients were included in this study. While CRP levels were lower in patients that were deceased, PCT levels were significantly higher in these patients. In patients with APACHE II score > 20 and PCT > 2 ng/ml, mortality was statistically very significantly higher compared with other patients. Logistical regression analysis showed that high PCT levels and APACHE II scores were important at predicting mortality in these patients. Conclusion: High PCT levels within 48 hours of burns is a predictor of mortality in these patients. Additional studies are required to correctly determine the cut-off value. A modified scoring system including APACHE II and PCT may be useful for better predicting mortality, although larger multi-centered studies are required. © 2016, E-Century Publishing Corporation. All rights reserved.en_US
dc.identifier.endpage6503en_US
dc.identifier.issn1940-5901
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84964221843en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage6497en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8114
dc.identifier.volume9en_US
dc.identifier.wosWOS:000377959900140en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherE-Century Publishing Corporationen_US
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01623
dc.subjectApache II scoreen_US
dc.subjectBurnen_US
dc.subjectC-reactive proteinen_US
dc.subjectProcalcitoninen_US
dc.titleDo early procalcitonine levels aid in predicting mortality in burn patients?en_US
dc.typeArticle
dspace.entity.typePublication

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