Neurosyphilis presenting as psychiatric symptoms: an unusual case report

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dc.contributor.authorMirsal, Hasan
dc.contributor.authorKalyoncu, Ayhan
dc.contributor.authorPektas, Oezkan
dc.contributor.authorBeyazyuerek, Mansur
dc.date.accessioned2024-07-12T21:44:18Z
dc.date.available2024-07-12T21:44:18Z
dc.date.issued2007en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractObjective: Neurosyphilis remains a differential diagnosis for a wide variety of psychiatric syndromes, including dementia, mood disorders and psychosis. However, the incidence of neurosyphilis presenting initially with psychiatric symptomalogy is unclear. In this article, a clinical case is reported so as to illustrate some of the issues involved. Case presentation: A 33-year-old married man was admitted because of a depressive episode associated with somatic preoccupations and a gradual loss of ability to function a year prior to his admission. The symptoms described above raised the question of an organic brain syndrome associated with the psychotic depression. Some laboratory and additional examinations were performed. Serological tests for syphilis were positive for both the hemagglutination test, Treponema pallidum hemaglutination (TPHA), and the immunofluorescent antibody test, fluorescent treponemal antibody-absorption (FTA-ABS). Based on these findings, the diagnosis of neurosyphilis was made. The patient was treated with benzathine penicillin (2 400 000 units i.m. once a week) for 3 weeks and venlafaxine (150 mg daily) and olanzapine (5 mg daily). His depression disappeared gradually, and he was discharged in partial remission. Conclusion: High-risk groups such as patients with neuropsychiatric diseases should be screened with serological tests so as to prevent morbidity and help eliminate syphilis.en_US
dc.identifier.doi10.1111/j.1601-5215.2007.00209.x
dc.identifier.endpage253en_US
dc.identifier.issn0924-2708
dc.identifier.issue4en_US
dc.identifier.pmid26952892en_US
dc.identifier.scopus2-s2.0-34447621622en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage251en_US
dc.identifier.urihttps://dx.doi.org/10.1111/j.1601-5215.2007.00209.x
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7711
dc.identifier.volume19en_US
dc.identifier.wosWOS:000248155600006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBLACKWELL PUBLISHINGen_US
dc.relation.ispartofACTA NEUROPSYCHIATRICAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY00051
dc.subjecthigh-risk groupsen_US
dc.subjectneurosyphilisen_US
dc.subjectpsychiatricen_US
dc.subjectsymptomsen_US
dc.subjecttreatmenten_US
dc.titleNeurosyphilis presenting as psychiatric symptoms: an unusual case reporten_US
dc.typeArticle
dspace.entity.typePublication

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