Comparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemia

Basit Öğe Kaydı
dc.authorid0000-0001-8944-0659en_US
dc.contributor.authorAydin A.
dc.contributor.authorGur E.
dc.contributor.authorErener-Ercan T.
dc.contributor.authorCan G.
dc.contributor.authorArvas A.
dc.date.accessioned2024-07-12T21:51:17Z
dc.date.available2024-07-12T21:51:17Z
dc.date.issued2017en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractWe compared the efficacy of ferrous sulfate (divalent) and ferric polymaltose (trivalent) compounds for the prophylaxis of iron-deficiency anemia (IDA). Study infants included exclusively breast milk-fed term infants. Subjects were divided randomly into 2 groups at 4 months of age and group 1 (n=56) received divalent and group 2 (n=56) received trivalent iron (Fe) preparation at a dose of 2 mg/kg/d for 5 months. At 9 months of age, after a 5-month prophylaxis, a significant increase was observed in hemoglobin (Hb), hematocrit, serum Fe levels, and transferrin saturation in both groups. However, group 1 had significantly higher Hb, hematocrit, mean corpuscular volume, Fe, and transferrin saturation than group 2 (11.7±0.6 g/dL, 34.6%±1.7%, 76.2±2.9 fL, 55.5±1.8 mcg, 20.8±3.9 g/L, respectively in group 1 vs. 11.3±0.5 g/dL, 33.5%±1.5%, 74.7±3.2 fL, 42.5±1.8 mcg, 14.1±7.5 g/L, respectively in group 2). No significant difference was found in ferritin values between the groups. Fe deficiency was found in 17 (30.3%) of the subjects in group 1, and 23 (41%) of subjects in group 2 whereas 5 (8.9%) subjects had IDA in group 1 and 12 (12%) in group 2 which were insignificant between groups. No significant difference was found with regard to side effects between 2 Fe preparations. Although divalent Fe therapy led to a higher Hb and serum Fe level, both ferrous and ferric Fe preparations were effective for prophylactic use in the prevention of Fe deficiency and IDA with comparable side effects. © Copyright 2017 Wolters Kluwer Health, Inc. All rights reserved.en_US
dc.identifier.doi10.1097/MPH.0000000000000967
dc.identifier.endpage499en_US
dc.identifier.issn1077-4114
dc.identifier.issue7en_US
dc.identifier.pmid28872486en_US
dc.identifier.scopus2-s2.0-85030765859en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage495en_US
dc.identifier.urihttps://dx.doi.org/10.1097/MPH.0000000000000967
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8254
dc.identifier.volume39en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams and Wilkinsen_US
dc.relation.ispartofJournal of Pediatric Hematology/Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02008
dc.subjectferric ironen_US
dc.subjectferrous ironen_US
dc.subjectiron deficiencyen_US
dc.subjectiron-deficiency anemiaen_US
dc.subjectprophylaxisen_US
dc.titleComparison of Different Iron Preparations in the Prophylaxis of Iron-deficiency Anemiaen_US
dc.typeArticle
dspace.entity.typePublication

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu