An infectious mononucleosis case
Küçük Resim Yok
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ORTADOGU AD PRES & PUBL CO
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Epstein-Barr virus (EBV) is transmitted through intimate contact and the portal of entry is usually the lympho-epithelial cells lining the oral cavity where a persistent infection is established. The virus-host interaction is usually sub-clinical in young children. A 20-month-old male presented with long-lasting high fever of unknown origin. Generalized lymphadenopathy and an exantematous rash on the back of the patient were detected on physical examination. Antibodies against EBV, rubella, CMV and HSV were detected in the initial blood samples and the avidity of IgG class antibodies was evaluated. Low avidity of EBV-VCA IgG was detected and, other serological tests for EBV were performed. Infectious mononucleosis was diagnosed upon positive test results. Previous studies reporte that, during infections by viruses that may cause latent infections, polyclonal B lymphocytes are activated, producing antibodies against other viruses. As a result, in patients with exanthematous rash, IgM and IgG class antibodies along with avidity tests should be evaluated for differential diagnosis.
Açıklama
Anahtar Kelimeler
herpesvirus 4, human, cytomegalovirus, simplexvirus, rubella
Kaynak
TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
27
Sayı
2
