Are increased carotid artery pulsatility and resistance indexes early signs of vascular abnormalities in young obese males?

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dc.authorid0000-0002-4936-3705en_US
dc.contributor.authorOzari, H. Onur
dc.contributor.authorOktenli, Cagatay
dc.contributor.authorCelik, Serkan
dc.contributor.authorTangi, Fatih
dc.contributor.authorIpcioglu, Osman
dc.contributor.authorTerekeci, Hakan M.
dc.contributor.authorTop, Cihan
dc.contributor.authorUzun, Mehmet
dc.contributor.authorSanisoglu, Yavuz S.
dc.contributor.authorNalbant, Selim
dc.date.accessioned2024-07-12T21:50:38Z
dc.date.available2024-07-12T21:50:38Z
dc.date.issued2012en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractPurpose: To provide insight into the factors by which obesity in itself may directly lead to early arterial damage, we aimed to determine early sonographic markers of obesity-related vascular dysfunction in young obese males. Methods: Thirty-five young obese males and 23 age-matched healthy male volunteers were recruited into the study. Common carotid artery pulsatility index and resistance index were calculated from blood flow velocities curves obtained by pulsed Doppler ultrasonography. Results: The mean pulsatility index, resistance index, body mass index, waist circumference, systolic and diastolic blood pressure, homeostasis model assessment for insulin resistance, plasma fasting glucose, insulin, C-peptide, triglycerides, low-density lipoprotein cholesterol, and high-sensitivity C-reactive protein were statistically higher in obese subjects than in healthy controls. Conclusions: Our results suggest that depressed vessel compliance and increased vascular resistance are features of young, obese, normotensive subjects independently of and in addition to cardiovascular risk factors. As changes in arterial wall properties may be incipient in young obese subjects, future studies will be required to demonstrate whether early intervention such as diet and exercise in this population can improve vascular functions. (C) 2012 Wiley Periodicals, Inc. J Clin Ultrasound, 2012en_US
dc.identifier.doi10.1002/jcu.21927
dc.identifier.endpage340en_US
dc.identifier.issn0091-2751
dc.identifier.issue6en_US
dc.identifier.pmid22532370en_US
dc.identifier.scopus2-s2.0-84862221470en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage335en_US
dc.identifier.urihttps://dx.doi.org/10.1002/jcu.21927
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8171
dc.identifier.volume40en_US
dc.identifier.wosWOS:000305061600003en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWILEY-BLACKWELLen_US
dc.relation.ispartofJOURNAL OF CLINICAL ULTRASOUNDen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY01849
dc.subjectDoppler ultrasonographyen_US
dc.subjectpulsatility indexen_US
dc.subjectresistance indexen_US
dc.subjectobesityen_US
dc.titleAre increased carotid artery pulsatility and resistance indexes early signs of vascular abnormalities in young obese males?en_US
dc.typeArticle
dspace.entity.typePublication

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