Comparison of conventional chest physiotherapy and oscillatory positive expiratory pressure therapy in primary ciliary dyskinesia

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dc.authorid0000-0002-0853-7932en_US
dc.authorid0000-0001-8239-4776en_US
dc.authorid0000-0002-0555-5932en_US
dc.authorid0000-0003-3105-0409en_US
dc.authorid0000-0002-5102-0031en_US
dc.authorid0000-0001-8829-3431en_US
dc.authorid0000-0002-9918-4705en_US
dc.authorid0000-0002-3639-879Xen_US
dc.authorid0000-0002-7420-9902en_US
dc.authorid0000-0001-8518-4715en_US
dc.authorid0000-0002-4317-2190en_US
dc.authorid0000-0003-0605-8871en_US
dc.contributor.authorBingöl, İbrahim
dc.contributor.authorGökdemir, Yasemin
dc.contributor.authorYılmaz Yegit, Cansu
dc.contributor.authorErgenekon, Pınar
dc.contributor.authorAtağ, Emine
dc.contributor.authorBaş İkizoğlu, Nilay
dc.contributor.authorErdem Eralp, Ela
dc.contributor.authorGencer, Kardelen
dc.contributor.authorK Saygı, Evrim
dc.contributor.authorKarakoç, Fazilet
dc.contributor.authorErsu, Refika
dc.contributor.authorKaradağ, Bülent
dc.date.accessioned2024-07-12T21:10:41Z
dc.date.available2024-07-12T21:10:41Z
dc.date.issued2020en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: Chest physiotherapy (CP) is a recommended treatment modality in primary ciliary dyskinesia (PCD). Objective: Primary aim was to compare the efficacy and safety of the conventional chest physiotherapy (CCP) and oscillatory positive expiratory pressure therapy (OPEPT). Secondary aims were to compare the exacerbation rate, time until the first exacerbation, patient compliance and comfort between the two CP methods. Methods: This is a 6 month randomized, controlled crossover trial. Patients >6 years of age with PCD were randomized into two groups, first group was assigned to OPEPT (Acapella®) for 3 months while second group was assigned to CCP. Groups were crossed over to the other modality after a 15-day washout period. Pulmonary function tests (PFTs) and compliance were monitored by monthly clinic visits. Results: There was a significant increase in FEV1 , FEF25-75 , and PEF values (p = .018, p = .020, and p = .016, respectively) in the OPEPT group and in FVC values (p = .007) in CCP group compared to baseline. However PFT increase at 3rd month was not superior to each other with both physiotherapy methods. Median acute pulmonary exacerbation rate and time period until the first exacerbation were similar in both groups (p = .821, p = .092, respectively). Comfort and effectiveness of OPEPT was higher than CCP according to patients (p = .029 and p = .042, respectively). There were no adverse effects with either therapy. Conclusions: OPEPT was as effective as CCP in PCD patients. OPEPT was more comfortable and effective than CCP according to patients. OPEPT might be an efficient alternative method for airway cleareance in PCD patients.en_US
dc.identifier.citationBingol, I., Gokdemir, Y., Yilmaz-Yegit, C., Ergenekon, P., Atag, E., Bas Ikizoglu, N., Erdem Eralp, E., Evkaya, A., Gencer, K., Saygi, E. K., Karakoc, F., Ersu, R., ve Karadag, B. (2020). Comparison of conventional chest physiotherapy and oscillatory positive expiratory pressure therapy in primary ciliary dyskinesia. Pediatric pulmonology, Pubmed. 55(12), s. 3414–3420.en_US
dc.identifier.doi10.1002/ppul.25099
dc.identifier.endpage3420en_US
dc.identifier.issn1099-0496
dc.identifier.issue12en_US
dc.identifier.pmid32997437en_US
dc.identifier.scopus2-s2.0-85093858531en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3414en_US
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/32997437/
dc.identifier.urihttps://doi.prg/10.1002/ppul.25099
dc.identifier.urihttps://hdl.handle.net/20.500.12415/4274
dc.identifier.volume55en_US
dc.identifier.wosWOS:000580650800001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorEvkaya, Ayça
dc.language.isoenen_US
dc.publisherPubMeden_US
dc.relation.ispartofPediatric Pulmonologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsCC0 1.0 Universal*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/publicdomain/zero/1.0/*
dc.snmzKY03220
dc.subjectchest physiotherapyen_US
dc.subjectoscillatory positive expiratory pressure therapyen_US
dc.subjectprimary ciliary dyskinesiaen_US
dc.titleComparison of conventional chest physiotherapy and oscillatory positive expiratory pressure therapy in primary ciliary dyskinesiaen_US
dc.typeArticle
dspace.entity.typePublication

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