Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?
Küçük Resim Yok
Tarih
2005
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
SAGE PUBLICATIONS LTD
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Comorbid alcohol dependence is common in patients with schizophrenia and is associated with a variety of serious adverse consequences. Although case reports exist concerning the positive impact of lamotrigine addition on clozapine treatment in resistant schizophrenia, a review of the literature fails to document any evidence regarding a combination of the two in the treatment of patients with schizophrenia and comorbid alcohol dependence. In the present study, we present three cases in which patients with resistant schizophrenia and comorbid alcohol use disorder were given lamotrigine to augment clozapine. Our findings suggest that clozapine plus lamotrigine may be helpful inreducing alcohol consumption and craving among patients with schizophrenia and comorbid alcohol dependence.
Açıklama
Anahtar Kelimeler
alcohol dependence, clozapine, craving, lamotrigine, schizophrenia
Kaynak
JOURNAL OF PSYCHOPHARMACOLOGY
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
19
Sayı
3
