Use of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?

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dc.contributor.authorKalyoncu, A
dc.contributor.authorMirsal, H
dc.contributor.authorPektas, O
dc.contributor.authorUnsalan, N
dc.contributor.authorTan, D
dc.contributor.authorBeyazyurek, M
dc.date.accessioned2024-07-12T21:51:22Z
dc.date.available2024-07-12T21:51:22Z
dc.date.issued2005en_US
dc.departmentMaltepe Üniversitesien_US
dc.description.abstractComorbid alcohol dependence is common in patients with schizophrenia and is associated with a variety of serious adverse consequences. Although case reports exist concerning the positive impact of lamotrigine addition on clozapine treatment in resistant schizophrenia, a review of the literature fails to document any evidence regarding a combination of the two in the treatment of patients with schizophrenia and comorbid alcohol dependence. In the present study, we present three cases in which patients with resistant schizophrenia and comorbid alcohol use disorder were given lamotrigine to augment clozapine. Our findings suggest that clozapine plus lamotrigine may be helpful inreducing alcohol consumption and craving among patients with schizophrenia and comorbid alcohol dependence.en_US
dc.identifier.doi10.1177/0269881105051542
dc.identifier.endpage305en_US
dc.identifier.issn0269-8811
dc.identifier.issn1461-7285
dc.identifier.issue3en_US
dc.identifier.pmid15888516en_US
dc.identifier.scopus2-s2.0-18844363205en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage301en_US
dc.identifier.urihttps://dx.doi.org/10.1177/0269881105051542
dc.identifier.urihttps://hdl.handle.net/20.500.12415/8260
dc.identifier.volume19en_US
dc.identifier.wosWOS:000228999800013en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSAGE PUBLICATIONS LTDen_US
dc.relation.ispartofJOURNAL OF PSYCHOPHARMACOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKY02023
dc.subjectalcohol dependenceen_US
dc.subjectclozapineen_US
dc.subjectcravingen_US
dc.subjectlamotrigineen_US
dc.subjectschizophreniaen_US
dc.titleUse of lamotrigine to augment clozapine in patients with resistant schizophrenia and comorbid alcohol dependence: a potent anti-craving effect?en_US
dc.typeArticle
dspace.entity.typePublication

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