Evaluation of Treatment Applications and Antibiotic Resistance Rates for Community Acquired Urinary Tract Infections in Turkey and a Review of the Literature

Basit Öğe Kaydı
dc.contributor.authorEroglu, Askin
dc.contributor.authorAlasehir, Elcin Akduman
dc.date.accessioned2024-07-12T21:00:28Z
dc.date.available2024-07-12T21:00:28Z
dc.date.issued2020en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractObjective: Increased extended-spectrum beta lactamase (ESBL) production is associated with higher rates of community-acquired strains in urinary tract infections (UTI) leading to an increase in the resistance rates, duration of treatment and costs. We aimed to investigate the resistance rates of ESBL-positive urine culture strains in our clinic, reviewed the literature and analysed antibiotics used in UTI treatment in outpatients in Turkiye. Materials and Methods: 2913 patients who were admitted to the outpatient clinics of Maltepe University Faculty of Medicine and Baskent University Faculty of Medicine were evaluated retrospectively. Data on prescribed antibiotics in outpatients with the diagnosis of UTI from all cities of Turkiye were collected through the Turkish Ministry of Health, Turkish Medicines and Medical Devices Agency. Results: Out of 563 ESBL-positive (19.3%) urine culture isolates, 450 (79.9%) were Escherichia coli and 89 (15.8%) were Klebsiella sp. Resistance rates were as follows: 98.8% to cefuroxime, 67.6% to ciprofloxacin, 12.5% to fosfomycin, 8.7% to amikacin, 1.4% to meropenem and 15% to nitrofurantoin. The most commonly prescribed antibiotics were ciprofloxacin (22.25%), fosfomycin (21.10%) and nitrofurantoin (12.82%). Conclusion: Our study suggests that the antibiotic resistance rates of most antibiotics prescribed for UTI in Turkiye are above the suggested rate of 10-20% to be used as empirical therapy. Updating and dissemination of guidelines for UTI in the light of antibiotic prescribing and resistance surveillance studies will contribute to the rational use of antibiotics in Turkiye.en_US
dc.identifier.citationEroglu, A, Alasehir, EA. (2020). Evaluation of Treatment Applications and Antibiotic Resistance Rates for Community Acquired Urinary Tract Infections in Turkey and a Review of the Literature. GALENOS YAYINCILIK. 7(2), s. 114-119.en_US
dc.identifier.doi10.4274/jus.galenos.2020.3532
dc.identifier.endpage119en_US
dc.identifier.issue2en_US
dc.identifier.startpage114en_US
dc.identifier.trdizinid363611en_US
dc.identifier.urihttps://doi.prg/10.4274/jus.galenos.2020.3532
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3381
dc.identifier.volume7en_US
dc.identifier.wosWOS:000537492900007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherGALENOS YAYINCILIKen_US
dc.relation.ispartofJOURNAL OF UROLOGICAL SURGERYen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY02087
dc.subjectCommunity-acquired urinary tract infectionen_US
dc.subjectEmpiric therapyen_US
dc.subjectExtended spectrum beta lactamaseen_US
dc.titleEvaluation of Treatment Applications and Antibiotic Resistance Rates for Community Acquired Urinary Tract Infections in Turkey and a Review of the Literatureen_US
dc.typeArticle
dspace.entity.typePublication

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