Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosis

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dc.authorid0000-0003-1078-0445en_US
dc.contributor.authorGürsu, Meltem
dc.contributor.authorYeğenağa, Itır
dc.contributor.authorTuğlular, Serhan
dc.contributor.authorDursun, Belda
dc.contributor.authorBek, Sibel Gökçay
dc.contributor.authorBardak, Simge
dc.contributor.authorOnan, Engin
dc.contributor.authorDemir, Serap
dc.contributor.authorDerici, Ülver
dc.contributor.authorDoğukan, Ayhan
dc.contributor.authorSevinç, Mustafa
dc.contributor.authorKoçyiğit, İsmail
dc.contributor.authorAltun, Eda
dc.contributor.authorHaras, Ali Burak
dc.contributor.authorAltıparmak, Mehmet Rıza
dc.contributor.authorTonbul, Halil Zeki
dc.date.accessioned2024-07-12T21:02:11Z
dc.date.available2024-07-12T21:02:11Z
dc.date.issued2022en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground: This study aimed to evaluate the etiologies, comorbidities, and outcomes of acute kidney injury (AKI) in Turkey and determine any potential diferences among diferent geographical parts of the country. Methods: This prospective observational study was conducted by the Acute Kidney Injury Working Group of the Turkish Society of Nephrology. Demographical and clinical data of patients with AKI at the time of diagnosis and at the 1st week and 1st, 3rd, and 6th months of diagnosis were evaluated to determine patient and renal survival and factors associated with patient prognosis. Results: A total of 776 patients were included (54.7% male, median age: 67 years). Prerenal etiologies, including dehydration, heart failure, and sepsis, were more frequent than other etiologies. 58.9% of the patients had at least one renal etiology, with nephrotoxic agent exposure as the most common etiology. The etiologic factors were mostly similar throughout the country. 33.6% of the patients needed kidney replacement therapy. At the 6th month of diagnosis, 29.5% of the patients had complete recovery; 34.1% had partial recovery; 9.5% developed end-stage kidney disease; and 24.1% died. The mortality rate was higher in the patients from the Eastern Anatolian region; those admitted to the intensive care unit; those with prerenal, renal, and postrenal etiologies together, stage 3 AKI, sepsis, cirrhosis, heart failure, and malignancy; those who need kidney replacement therapy; and those without chronic kidney disease than in the other patients. Conclusion: Physicians managing patients with AKI should be alert against dehydration, heart failure, sepsis, and nephrotoxic agent exposure. Understanding the characteristics and outcomes of patients with AKI in their countries would help prevent AKI and improve treatment strategies.en_US
dc.identifier.citationGürsu, M., Yeğenağa, I., Tuğlular, S. and at all. (2022). Acute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosis. BMC Nephrology, 23(326), p.1-15.en_US
dc.identifier.doi10.1186/s12882-022-02933-1
dc.identifier.endpage15en_US
dc.identifier.issue326en_US
dc.identifier.pmid36199011en_US
dc.identifier.scopus2-s2.0-85139277267en_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.prg/10.1186/s12882-022-02933-1
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3591
dc.identifier.volume23en_US
dc.identifier.wosWOS:000864294300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYeğenağa, Itır
dc.language.isoenen_US
dc.publisherBMC Nephrologyen_US
dc.relation.ispartofBMC Nephrologyen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY00438
dc.subjectAcute kidney injuryen_US
dc.subjectEtiologyen_US
dc.subjectKidney replacement therapyen_US
dc.subjectSurvivalen_US
dc.titleAcute kidney injury in Turkey: epidemiological characteristics, etiology, clinical course, and prognosisen_US
dc.typeArticle
dspace.entity.typePublication

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