Comparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patients

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dc.authorid0000-0002-0717-1756en_US
dc.contributor.authorUzun, Kübra Nur
dc.contributor.authorCıncık, Mehmet
dc.contributor.authorSelam, Belgin
dc.contributor.authorTakmaz, Özgüç
dc.contributor.authorUyar, Esra
dc.date.accessioned2024-07-12T21:05:00Z
dc.date.available2024-07-12T21:05:00Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractObjective: To compare the rates of blastocyst stage development between embryos fertilized after one (MPN) or more than two pronucleus (PN) (3PN, 4PN-multiPN) with those after 2PN in the same patients. Material and Methods: The embryos of patients who had both abnormal PN (MPN, 3PN or 4PN) and normal fertilized (2PN) embryos after intracytoplasmic sperm injection (ICSI) fertilization, were followed with a time-lapse system following the ICSI procedure. The rates of reaching the blastocyst stage were compared between normal and abnormally fertilized embryos. Results: One thousand eight hundred and twenty oocytes were collected from 140 patients and 1280 (70.3%) of them were fertilized. MPN, 2PN and 3PN, 4PN (multiPN) ratios of the embryos in the pronuclear stage were 11.4%, 83.13% and 5.47%, respectively. The rates of reaching the blastocyst stage among these embryos were 17.1%, 60.8% and 42.8% for MPN, 2PN and multiPN, respectively. The proportion reaching blastocyst development was significantly higher following 2PN compared to those after MPN and multiPN (p<0.05). Embryos developing after multiPN had significantly higher rates of reaching the blastocyst stage compared to those after MPN (p<0.01). Conclusion: The majority of abnormally pronucleated embryos arrest without reaching the blastocyst stage. MultiPN embryos have a higher rate of blastocyst development than MPN embryos. (J Turk Ger Gynecol Assoc 2021; 22: 120-6)en_US
dc.identifier.citationUzun, K.N., Cıncık, M., Selam, B., Takmaz,. Ö. ve Uyar, E. (2021)Comparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patients. Journal of the Turkish-German Gynecological Association, Erkan Mor. 22(2), s. 120-126.en_US
dc.identifier.doi10.4274/jtgga.galenos.2020.2020.0033
dc.identifier.endpage126en_US
dc.identifier.issn1309-0380
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85107985056en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage120en_US
dc.identifier.trdizinid483150en_US
dc.identifier.uri10.4274/jtgga.galenos.2020.2020.0033
dc.identifier.urihttps://doi.prg/10.4274/jtgga.galenos.2020.2020.0033
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3861
dc.identifier.volume22en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorCıncık, Mehmet
dc.language.isoenen_US
dc.publisherErkan Moren_US
dc.relation.ispartofJournal of the Turkish-German Gynecological Associationen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY02078
dc.subjectBlastocysten_US
dc.subjectICSIen_US
dc.subjectMPNen_US
dc.subjectmultiPNen_US
dc.subjecttime-lapseen_US
dc.titleComparison of the rates for reaching the blastocyst stage between normal and abnormal pronucleus embryos monitored by a time-lapse system in IVF patientsen_US
dc.typeArticle
dspace.entity.typePublication

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