Disrupted latent decision processes in medication-free pediatric OCD patients
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
ELSEVIER SCIENCE BV
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Decision-making in Obsessive Compulsive Disorder has typically been investigated in the adult population. Computational approaches have recently started to get integrated into these studies. However, decision-making research in pediatric OCD populations is scarce. Methods: We investigated latent decision processes in 21 medication-free pediatric OCD patients and 23 healthy control participants. We hypothesized that OCD patients would be more cautious and less efficient in evidence accumulation than controls in a two alternative forced choice (2AFC) task. Results: Pediatric OCD patients were less efficient than controls in accumulating perceptual evidence and showed a tendency to be more cautious. In comparison to post-correct decisions, OCD patients increased decision thresholds after erroneous decisions, whereas healthy controls decreased decision thresholds. These changes were coupled with weaker evidence accumulation after errors in both groups. Limitations: The small sample size limited the power of the study. Conclusions: Our results demonstrate poorer decision-making performance in pediatric OCD patients at the level of latent processes, specifically in terms of evidence accumulation. (C) 2016 Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Decision making, Hierarchical Drift Diffusion Model, Obsessive Compulsive Disorder, Children
Kaynak
JOURNAL OF AFFECTIVE DISORDERS
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
207
