Quality of Life of Individuals with Bipolar Disorder and Schizophrenia

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dc.authoridALPTEKIN, KOKSAL/0000-0002-7601-9002;en_US
dc.contributor.authorÇelik, Hidayet Ece Arat
dc.contributor.authorCeylan, Deniz
dc.contributor.authorBagci, Basak
dc.contributor.authorAkdede, Berna Binnur
dc.contributor.authorAlptekin, Koksal
dc.contributor.authorÖzerdem, Ayşegül
dc.date.accessioned2024-07-12T21:37:17Z
dc.date.available2024-07-12T21:37:17Z
dc.date.issued2022en_US
dc.department[Belirlenecek]en_US
dc.description.abstractIntroduction: Quality of life (QoL) is a concept defined as a subjective perception of one's position in life and is negatively affected in many psychiatric illnesses such as bipolar disorder (BD) and schizophrenia (SCZ). It is hypothesized that therapeutic approaches based on QoL can increase the patient's adherence to treatment and contribute to a satisfactory life. This study aimed to compare the QoL of individuals having BD and schizophrenia with that of healthy controls (HCs) and to investigate the impact of the state of remission on QoL.Method: The World Health Organization QoL Scale-Short Form (WHOQOL-Bref) was administered to individuals with BD (n=124) and SCZ (n=74) and to HCs (n=81) to evaluate QoL. The WHOQOL-Bref subscale and total scores were compared between the groups using multifactor analysis of covariance (MANCOVA) by considering age and education level as the covariates. Then, the patient groups were compared using MANCOVA based on the state of remission by taking age, level of education, and Global Assessment of Functioning scores as the covariates. The relationship between clinical features and QoL scores was evaluated using correlation analysis, and linear regression analysis was applied for the variables that were found to be significant.Results: It was found that individuals with SCZ or BD had lower WHOQOL-Bref psychological, social, and total scores than HCs. Those with SCZ additionally had lower physical and environmental subscale scores than HCs. Furthermore, those with SCZ had lower WHOQOL-Bref physical, psychological, social, and total scores than individuals with BD. There was no significant difference in WHOQOL-Bref scores between individuals with BD and SCZ in the remission period. WHOQOL-Bref physical, psychological, and total scores were found to be significantly lower in unremitted BD patients when compared with remitted BD patients. Unremitted BD patients were found to have significantly lower WHOQOL-Bref psychological, environmental, and total scale scores than unremitted SCZ patients. Conclusion: It can be concluded that the QoL of individuals with BD is between that of healthy individuals and those with SCZ. However, unremitted BD patients have lower QoL than unremitted SCZ patients. Both patient groups display similar features during remission. Identifying the similarities and differences in terms of QoL in both patient groups is of great importance to develop the best type of treatment for the patients.en_US
dc.identifier.doi10.29399/npa.28089
dc.identifier.endpage314en_US
dc.identifier.issn1300-0667
dc.identifier.issn1309-4866
dc.identifier.issue4en_US
dc.identifier.pmid36514519en_US
dc.identifier.scopus2-s2.0-85142519105en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage309en_US
dc.identifier.trdizinid1172609en_US
dc.identifier.urihttps://doi.org/10.29399/npa.28089
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1172609
dc.identifier.urihttps://hdl.handle.net/20.500.12415/6734
dc.identifier.volume59en_US
dc.identifier.wosWOS:000891291800010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTurkish Neuropsychiatry Assoc-Turk Noropsikiyatri Dernegien_US
dc.relation.ispartofNoropsikiyatri Arsivi-Archives of Neuropsychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY04076
dc.subjectBipolar Disorderen_US
dc.subjectSchizophreniaen_US
dc.subjectQuality Of Lifeen_US
dc.titleQuality of Life of Individuals with Bipolar Disorder and Schizophreniaen_US
dc.typeArticle
dspace.entity.typePublication

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