Histologic findings of corneal buttons in decompensated corneas with toxic anterior segment syndrome after cataract surgery
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
Attribution-NonCommercial-NoDerivs 3.0 United States
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
Purpose: To report the histologic findings of penetrating keratoplasty buttons in decompensated corneas with toxic anterior segment syndrome (TASS) after a cataract surgery is performed. Methods: We evaluated the histologic findings of 16 corneal buttons of 16 patients who exhibited decompensation findings because of TASS by means of light microscopy. The patients were classified into 3 groups: The first group consisted of 5 corneal buttons with mild symptoms in which the central corneal thicknesses (CCTs) were #650 mm, and the visual acuities (VAs) were $0.1. The second group consisted of 7 corneal buttons that exhibited moderate symptoms in which the CCTs were between 650 and 750 mm and the VAs were between 0.1 and 0.03. The third group consisted of 4 corneal buttons that had severe symptoms in which the CCTs were $750 mm and the VAs were #0.03. Results: Light microscopy showed endothelial cell loss, vacuolated and thinned epithelial cell layers, disturbed collagen bonds, and Descemet membrane invaginations in patients in group I. Group II corneal buttons exhibited inflammatory cells (lymphocytes) and extended intercellular space between the epithelial cells, wrinkled Bowman membrane separated from the stroma in some local areas, stromal edema, and early vascularization. In group III, endothelial and epithelial cell layer loss, wrinkled Descemet and Bowman membranes, inflammatory cells, and structurally disturbed collagen bonds located beneath the Bowman membrane, and a greater amount of vascularization in the area of inflammation were observed. Conclusions: The results of the histologic evaluation of the decompensated corneas caused by the TASS are compatible with the clinical severity of the disease. In mild cases, the histologic findings were insignificant; however, when the clinical situation deteriorated, histologic findings became increasingly worse.
Açıklama
Anahtar Kelimeler
toxic anterior segment syndrome, penetrating keratoplasty, corneal buttons, histologic evaluation
Kaynak
Cornea
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
32
Sayı
10
Künye
Arslan, O. Ş., Tunç, Z., Uçar, D., Seçkin, İ., Cicik, E., Kalem, H., Şencan, S. ve Hepokur, M. (2013). Histologic findings of corneal buttons in decompensated corneas with toxic anterior segment syndrome after cataract surgery. Cornea, Lippincott Williams & Wilkins. 32(10), s. 1387-1390.
