Histologic findings of corneal buttons in decompensated corneas with toxic anterior segment syndrome after cataract surgery

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dc.authorid0000-0001-6359-4799en_US
dc.authorid0000-0002-3469-7307en_US
dc.authorid0000-0003-4381-2597en_US
dc.authorid0000-0002-7775-9053en_US
dc.authorid0000-0002-0934-8084en_US
dc.contributor.authorArslan, Osman Şevki
dc.contributor.authorUçar, Didar
dc.contributor.authorSeçkin, İsmail
dc.contributor.authorCicik, Erdoğan
dc.contributor.authorKalem, Hande
dc.contributor.authorHepokur, Mustafa
dc.date.accessioned2024-07-12T21:03:05Z
dc.date.available2024-07-12T21:03:05Z
dc.date.issued2013en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractPurpose: To report the histologic findings of penetrating keratoplasty buttons in decompensated corneas with toxic anterior segment syndrome (TASS) after a cataract surgery is performed. Methods: We evaluated the histologic findings of 16 corneal buttons of 16 patients who exhibited decompensation findings because of TASS by means of light microscopy. The patients were classified into 3 groups: The first group consisted of 5 corneal buttons with mild symptoms in which the central corneal thicknesses (CCTs) were #650 mm, and the visual acuities (VAs) were $0.1. The second group consisted of 7 corneal buttons that exhibited moderate symptoms in which the CCTs were between 650 and 750 mm and the VAs were between 0.1 and 0.03. The third group consisted of 4 corneal buttons that had severe symptoms in which the CCTs were $750 mm and the VAs were #0.03. Results: Light microscopy showed endothelial cell loss, vacuolated and thinned epithelial cell layers, disturbed collagen bonds, and Descemet membrane invaginations in patients in group I. Group II corneal buttons exhibited inflammatory cells (lymphocytes) and extended intercellular space between the epithelial cells, wrinkled Bowman membrane separated from the stroma in some local areas, stromal edema, and early vascularization. In group III, endothelial and epithelial cell layer loss, wrinkled Descemet and Bowman membranes, inflammatory cells, and structurally disturbed collagen bonds located beneath the Bowman membrane, and a greater amount of vascularization in the area of inflammation were observed. Conclusions: The results of the histologic evaluation of the decompensated corneas caused by the TASS are compatible with the clinical severity of the disease. In mild cases, the histologic findings were insignificant; however, when the clinical situation deteriorated, histologic findings became increasingly worse.en_US
dc.identifier.citationArslan, O. Ş., Tunç, Z., Uçar, D., Seçkin, İ., Cicik, E., Kalem, H., Şencan, S. ve Hepokur, M. (2013). Histologic findings of corneal buttons in decompensated corneas with toxic anterior segment syndrome after cataract surgery. Cornea, Lippincott Williams & Wilkins. 32(10), s. 1387-1390.en_US
dc.identifier.doi10.1097/ICO.0b013e3182a0d030
dc.identifier.endpage1390en_US
dc.identifier.issn0277-3740
dc.identifier.issn1536-4798
dc.identifier.issue10en_US
dc.identifier.pmid23974897en_US
dc.identifier.scopus2-s2.0-84886085882en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1387en_US
dc.identifier.urihttps://journals.lww.com/corneajrnl/Fulltext/2013/10000/Histologic_Findings_of_Corneal_Buttons_in.17.aspx
dc.identifier.urihttps://doi.prg/10.1097/ICO.0b013e3182a0d030
dc.identifier.urihttps://hdl.handle.net/20.500.12415/3629
dc.identifier.volume32en_US
dc.identifier.wosWOS:000324747000019en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTunç, Zeki
dc.institutionauthorŞencan, Sadık
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCorneaen_US
dc.relation.publicationcategoryUluslararası Hakemli Dergide Makale - Kurum Öğretim Elemanıen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.snmzKY00564
dc.subjecttoxic anterior segment syndromeen_US
dc.subjectpenetrating keratoplastyen_US
dc.subjectcorneal buttonsen_US
dc.subjecthistologic evaluationen_US
dc.titleHistologic findings of corneal buttons in decompensated corneas with toxic anterior segment syndrome after cataract surgeryen_US
dc.typeArticle
dspace.entity.typePublication

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