The connection between MCI and Alzheimer disease: neurocognitive clues

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dc.authorid0000-0003-3868-3137en_US
dc.authorid0000-0003-2016-9965en_US
dc.authorid0000-0002-2887-9235en_US
dc.contributor.authorBatum, Kübra
dc.contributor.authorÇınar, Nilgün
dc.contributor.authorŞahin, Şevki
dc.contributor.authorÇakmak, Miraç Ayşen
dc.contributor.authorKarşıdağ, Sibel
dc.date.accessioned2024-07-12T21:43:19Z
dc.date.available2024-07-12T21:43:19Z
dc.date.issued2015en_US
dc.departmentFakülteler, Tıp Fakültesien_US
dc.description.abstractBackground/aim: Mild cognitive impairment (MCI) is defined as a pathological stage between 'healthy aging' and 'dementia'. In this study, cases of MCI were compared with early-stage Alzheimer disease (AD) and age-related cognitive decline (ARCD) in terms of cognitive profiles in order to find a connection between MCI and AD. Materials and methods: Patients who were comparable in terms of age and sex and who met the criteria of MCI, ARCD, or early-stage AD were included in the study retrospectively. Wechsler memory scale, executive function, visuospatial, language, and memory tests were applied to all subjects. Additionally, all patients completed a mini-mental state examination test, geriatric depression scale, and activities of daily living scale. Results: Complex attention tests and long-term memory tests were more impaired in MCI patients when compared with ARCD. However, there were no significant differences between the MCI and ARCD cases in activities of daily living. Memory and executive functions were more deteriorated in patients with AD in comparison to MCI. Conclusion: During the follow-up period of ARCD, impairment in orientation, complex attention, and long-term memory should suggest the diagnosis of MCI. When personal information and executive functions are affected in MCI, AD should be carefully considered.en_US
dc.identifier.doi10.3906/sag-1404-179
dc.identifier.endpage1140en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue5en_US
dc.identifier.pmid26738359en_US
dc.identifier.scopus2-s2.0-84943240956en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1137en_US
dc.identifier.trdizinid180125en_US
dc.identifier.urihttps://dx.doi.org/10.3906/sag-1404-179
dc.identifier.urihttps://hdl.handle.net/20.500.12415/7576
dc.identifier.volume45en_US
dc.identifier.wosWOS:000362526300024en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKY03733
dc.subjectDementiaen_US
dc.subjectMCIen_US
dc.subjectcognitive testsen_US
dc.subjectforgetfulnessen_US
dc.titleThe connection between MCI and Alzheimer disease: neurocognitive cluesen_US
dc.typeArticle
dspace.entity.typePublication

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